Search Results
Overview
| Uniprot ID | A0A0G2JSM8 |
|---|---|
| Protein Name | Cell division control protein 42 homolog |
| Gene Name | Cdc42 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 144 | ITPETAEKLARDLKA |
| 153 | ARDLKAVKYVECSAL |
Function
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state
Protein Sequence
10
MQTIKCVVVG
20
DGAVGKTCLL
30
ISYTTNKFPS
40
EYVPTVFDNY
50
AVTVMIGGEP
60
YTLGLFDTAG
70
QEDYDRLRPL
80
SYPQTDVFLV
90
CFSVVSPSSF
100
ENVKEKWVPE
110
ITHHCPKTPF
120
LLVGTQIDLR
130
DDPSTIEKLA
140
KNKQKPITPE
150
TAEKLARDLK
160
AVKYVECSAL
170
TQRGLKNVFD
180
EAILAALEPP
190
ETQPKRKCCI
F
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0030496 | midbody |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0003925 | G protein activity |
| Molecular Function | GO:0005525 | GTP binding |
| Molecular Function | GO:0019901 | protein kinase binding |
| Biological Process | GO:0009653 | anatomical structure morphogenesis |
| Biological Process | GO:0051130 | positive regulation of cellular component organization |
| Biological Process | GO:0007264 | small GTPase-mediated signal transduction |
Reference
[1] Yao Y, Bade R, Li G, Zhang A, Zhao H et al.. Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats.. Cell Mol Neurobiol 43(5):1989-2004. 2023 Jul. PMID: 36030297.
[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.