Search Results
Overview
| Uniprot ID | A0A0G2JSV3 |
|---|---|
| Protein Name | Ribose-phosphate pyrophosphokinase 1 |
| Gene Name | Prps1l3 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 176 | SPDAGGAKRVTSIAD |
Function
Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis
Protein Sequence
10
MPNIKIFSGS
20
SHQDLSQKIA
30
DRLGLELGKV
40
VTKKFSNQET
50
CVEIGESVRG
60
EDVYIVQSGC
70
GEINDNLMEL
80
LIMINACKIA
90
SASRVTAVIP
100
CFPYARQDKK
110
DKSRAPISAK
120
LVANMLSVAG
130
ADHIITMDLH
140
ASQIQGFFDI
150
PVDNLYAEPA
160
VLKWIRENIS
170
EWKNCTIVSP
180
DAGGAKRVTS
190
IADRLNVDFA
200
LIHKERKKAN
210
EVDRMVLVGD
220
VKDRVAILVD
230
DMADTCGTIC
240
HAADKLLSAG
250
ATRVYAILTH
260
GIFSGPAISR
270
INNACFEAVV
280
VTNTIPQEDK
290
MKHCSKIQVI
300
DISMILAEAI
310
RRTHNGESVS
YLFSHVPL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0002189 | ribose phosphate diphosphokinase complex |
| Molecular Function | GO:0043531 | ADP binding |
| Molecular Function | GO:0016208 | AMP binding |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0019003 | GDP binding |
| Molecular Function | GO:0016301 | kinase activity |
| Molecular Function | GO:0000287 | magnesium ion binding |
| Molecular Function | GO:0004749 | ribose phosphate diphosphokinase activity |
| Biological Process | GO:0006015 | 5-phosphoribose 1-diphosphate biosynthetic process |
| Biological Process | GO:0006167 | AMP biosynthetic process |
| Biological Process | GO:0031100 | animal organ regeneration |
| Biological Process | GO:0006164 | purine nucleotide biosynthetic process |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.