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Overview

Uniprot ID	A0A0G2JVH4
Protein Name	MICOS complex subunit MIC60
Gene Name	Immt
Organism	Rattus norvegicus

Kla Sites from experimental identification

Position	Flanking peptide
102	YTVPLPKKPIQSGPL
446	IQAEQDRKVEEVRDA

Function

Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane

Protein Sequence

10 MLRACQLSGV 20 TVAAQSCLCG 30 KFVLRPLRPC 40 RRYSTSSSSG 50 VTAGKIAGAG 60 LLFVGGGIGG 70 TILYAKWDSH 80 FRESVEKTIP 90 YSDKLFGMVL 100 GSAPYTVPLP 110 KKPIQSGPLK 120 ISSVSEVMTD 130 SELPMAQTQE 140 TNGDTPASAA 150 GDPAPEVEHE 160 DTINTECPNT 170 DEGTSTFVTA 180 EEASSSSVRE 190 RPPEEVAARL 200 AQQEKQEQVE 210 MESLAKSLED 220 ALNQTATVTR 230 QTITAQNAAV 240 QAVKAHSSTL 250 KTAMDNSEIA 260 GEKKSAQWRT 270 VEGALKERRK 280 AVDEAADALL 290 KAKEELEKMK 300 TIIEDAKKRE 310 IAGATPYITA 320 AEEKLHSMIV 330 DLDSVVKKVQ 340 AAQSEAKVVS 350 QYHELVVQAR 360 DDFRKELDSI 370 TPDITPGWKG 380 MTGTLSTDDL 390 NALIAHAHRR 400 IDQLNRELAQ 410 QKATEKQHIE 420 LALERQKLEE 430 KRAFDSAVAK 440 ALEHHRSEIQ 450 AEQDRKVEEV 460 RDAMENEMRT 470 QLRRQAAAHT 480 DHLRDVLKVQ 490 EQELKFEFEQ 500 DLSEKLSEQE 510 LEFHRRSQEQ 520 MDNFTLDINT 530 AYARLRGIEQ 540 AVQSHAVAEE 550 EARKAHQLWL 560 SVEALKYSMK 570 TSSAEMPTIP 580 LGSAVEAIRV 590 SCSDNEFTQA 600 LTAAIPPESL 610 TRGVYSEETL 620 RARFYAVQKL 630 AGRVAMIDET 640 KNSLYQYFLS 650 YLQSLLLFPP 660 KQLKPPAELY 670 PEDINTFKLL 680 SYASYCIEHG 690 DLELAAKFVN 700 QLKGESRRVA 710 QDWLKEARMT 720 LETKQIVEIL 730 TTYASAVGIG TTQVQQE

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005743	mitochondrial inner membrane

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.