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Overview

Uniprot ID	A0A0G2JWA5
Protein Name	Sarcolemmal membrane-associated protein
Gene Name	Slmap
Organism	Rattus norvegicus

Kla Sites from experimental identification

Position	Flanking peptide
63	ALVWFDHKTSKFYLQ

Function

Associates with the striatin-interacting phosphatase and kinase (STRIPAK) core complex, forming the extended (SIKE1:SLMAP)STRIPAK complex. The (SIKE1:SLMAP)STRIPAK complex dephosphorylates STK3 leading to the inhibition of Hippo signaling and the control of cell growth. May play a role during myoblast fusion

Protein Sequence

10 MPSALAIFTC 20 RPNSHPFQER 30 HVYLDEPIKI 40 GRSVARCRPA 50 QNNATFDCKV 60 LSRNHALVWF 70 DHKTSKFYLQ 80 DTKSSNGTFI 90 NSQRLSRGSE 100 ESPPCEILSG 110 DIIQFGVDVT 120 ENTRKVTHGC 130 IVSTIKLFLP 140 DGMEARLRSD 150 VIHAPLPSPV 160 DKVAANTPSM 170 YSQELFQLSQ 180 YLQEALHREQ 190 MLEQKLATLQ 200 RLLAITQEAS 210 DTSWQALIDE 220 DRLLSRLEVM 230 GNQLQACSKN 240 QTEDSLRKEL 250 VALQEDKHSY 260 ETTAKESLRR 270 VLQEKIEVVR 280 KLSEVERSLS 290 NTEDECTHLR 300 EMNERTQEEL 310 RELANKYNGA 320 VNEIKDLSDK 330 LKAAEGKQEE 340 IQQKGQAEKK 350 ELQAKIDDME 360 EKEQELQAKI 370 EALQADNDFT 380 NERLTALQVR 390 LEPLQEKTLK 400 ECSSLGIQVD 410 DFLPKINGST 420 EKEKLMVQGH 430 LTKVVEESKL 440 SKENQAKAKE 450 SDLSDTLSPS 460 KEKSSDDTTD 470 AQMDEQDLNE 480 PLAKVSLLKD 490 DLQGTQAETE 500 AKQDTQHLRK 510 ELVEAQELAR 520 ASKQKCFDLQ 530 ALLEEERKAY 540 RNQVEESAKQ 550 IQVLQVQLQR 560 LHMDMENLQE 570 EKDTEISSTR 580 DKLLSAQDEI 590 LLLHQAAAKA 600 VSERDTDFMS 610 LQEELKKVRA 620 ELEGWRKAAS 630 EYEEEIRSLQ 640 STFQLRCQQC 650 EVQQREEATR 660 LQGELEKLKK 670 EWDVLENECR 680 SLKKENVLLS 690 SELQRQEKEL 700 HNSQKQSLEL 710 TSDLSILQMT 720 RKELENQMGS 730 LKEQHLRDEA 740 DLKTLLSKAE 750 NQAKDVQKEY 760 EKTQTVLSEL 770 KLKFEMTEQE 780 KQSITDELKQ 790 CKDNLKLLRE 800 KGNNPSILQP 810 VPAVFIGLFL 820 AFLFWCFGPL W

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005813	centrosome
Cellular Component	GO:0005789	endoplasmic reticulum membrane
Cellular Component	GO:0031966	mitochondrial membrane
Cellular Component	GO:0042383	sarcolemma

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.