Search Results
Overview
| Uniprot ID | A0A0G2JWM2 |
|---|---|
| Protein Name | NAD-dependent protein deacetylase |
| Gene Name | Sirt2 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 195 | TMSWMKEKIFSEATP |
| 203 | IFSEATPKCEKCQNV |
| 270 | TPRLLINKEKTGQTD |
| 322 | ADLLGWKKELEDLVR |
| 360 | RKSPPPAKEAARTKE |
Function
NAD-dependent protein deacetylase
Protein Sequence
10
METQDSDSDT
20
EGGATGGEAE
30
MDFLRNLFTQ
40
TLGLGSQKER
50
LLDELTLEGV
60
TRYMQSERCR
70
RVICLVGAGI
80
STSAGIPDFR
90
SPSTGLYANL
100
EKYHLPYPEA
110
IFEISYFKKH
120
PEPFFALAKE
130
LYPGQFKPTI
140
CHYFIRLLKE
150
KGLLLRCYTQ
160
NIDTLERVAG
170
LEPQDLVEAH
180
GTFYTSHCVN
190
TSCGKEYTMS
200
WMKEKIFSEA
210
TPKCEKCQNV
220
VKPDIVFFGE
230
NLPPRFFSCM
240
QSDFSKVDLL
250
IIMGTSLQVQ
260
PFASLISKAP
270
LATPRLLINK
280
EKTGQTDPFL
290
GMMMGLGGGM
300
DFDSKKAYRD
310
VAWLGDCDQG
320
CLALADLLGW
330
KKELEDLVRR
340
EHANIDAQSG
350
SQASNPSATV
360
SPRKSPPPAK
370
EAARTKEKEE
H
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005814 | centriole |
| Cellular Component | GO:0005694 | chromosome |
| Cellular Component | GO:0030426 | growth cone |
| Cellular Component | GO:0005874 | microtubule |
| Cellular Component | GO:0030496 | midbody |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0033010 | paranodal junction |
| Cellular Component | GO:0043204 | perikaryon |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0043220 | Schmidt-Lanterman incisure |
| Cellular Component | GO:0005819 | spindle |
| Molecular Function | GO:0017136 | histone deacetylase activity, NAD-dependent |
| Molecular Function | GO:0070403 | NAD+ binding |
| Molecular Function | GO:0042903 | tubulin deacetylase activity |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0051301 | cell division |
| Biological Process | GO:0051321 | meiotic cell cycle |
| Biological Process | GO:0022011 | myelination in peripheral nervous system |
| Biological Process | GO:0051093 | negative regulation of developmental process |
| Biological Process | GO:0042981 | regulation of apoptotic process |
| Biological Process | GO:0045595 | regulation of cell differentiation |
| Biological Process | GO:0031641 | regulation of myelination |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.