Search Results

Overview

Uniprot IDA0A0G2JYW3
Protein NameClathrin light chain
Gene NameClta
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
130 ALDANSRKQEAEWKE
136 RKQEAEWKEKAVKEL
141 EWKEKAVKELEEWYA
156 RQDEQLQKTKASNRV
211 RLCDFNPKSSKQAKD
230 RSVLISLKQAPLVH*

Function

Clathrin is the major protein of the polyhedral coat of coated pits and vesicles

Protein Sequence

10 MAELDPFGAP 20 AGAPGGPALG 30 NGVAGAGEED 40 PAAAFLAQQE 50 SEIAGIENDE 60 AFAILDGGAP 70 GPQAHGEPPG 80 GPDAVDGVMN 90 GEYYQESNGP 100 TDSYAAISEV 110 DRLQSEPESI 120 RKWREEQTER 130 LEALDANSRK 140 QEAEWKEKAV 150 KELEEWYARQ 160 DEQLQKTKAS 170 NRVADEAFYK 180 QPFADVIGYV 190 AAEEAFVNDI 200 DESSPGTEWE 210 RVARLCDFNP 220 KSSKQAKDVS 230 RMRSVLISLK QAPLVH

Gene Ontology

Classification GO ID Description
Cellular Component GO:0030132 clathrin coat of coated pit
Cellular Component GO:0030130 clathrin coat of trans-Golgi network vesicle
Molecular Function GO:0005198 structural molecule activity
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0016192 vesicle-mediated transport

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.

[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.