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Overview

Uniprot ID	A0A0G2JZS2
Protein Name	Polyadenylate-binding protein
Gene Name	Pabpc1
Organism	Rattus norvegicus

Kla Sites from experimental identification

Position	Flanking peptide
188	AELGARAKEFTNVYI
512	VRTVPQYKYAAGVRN

Function

Binds the poly(A) tail of mRNA

Protein Sequence

10 MNPSAPSYPM 20 ASLYVGDLHP 30 DVTEAMLYEK 40 FSPAGPILSI 50 RVCRDMITRR 60 SLGYAYVNFQ 70 QPADAERALD 80 TMNFDVIKGK 90 PVRIMWSQRD 100 PSLRKSGVGN 110 IFIKNLDKSI 120 DNKALYDTFS 130 AFGNILSCKV 140 VCDENGSKGY 150 GFVHFETQEA 160 AERAIEKMNG 170 MLLNDRKVFV 180 GRFKSRKERE 190 AELGARAKEF 200 TNVYIKNFGE 210 DMDDERLKEL 220 FGKFGPALSV 230 KVMTDESGKS 240 KGFGFVSFER 250 HEDAQKAVDE 260 MNGKELNGKQ 270 IYVGRAQKKV 280 ERQTELKRKF 290 EQMKKKNVDS 300 SDRCGVNLYV 310 KNLDDGIDDE 320 RLRKEFSPFG 330 TITSAKVMME 340 GGRSKGFGFV 350 CFSSPEEATK 360 AVTEMNGRIV 370 ATKPLYVALA 380 QRKEERQAHL 390 TNQYMQRMAS 400 VRAVPNPVIN 410 PYQPAPPSGY 420 FMAAIPQTQN 430 RAAYYPPSQI 440 AQLRPSPRWT 450 AQGARPHPFQ 460 NMPGAIRPAA 470 PRPPFSTMRP 480 ASSQVPRVMS 490 TQPNTSTQTM 500 GPRPAAAATA 510 ATPAVRTVPQ 520 YKYAAGVRNP 530 QQHLNAQPQV 540 TMQQPAVHVQ 550 GQEPLTASML 560 ASAPPQEQKQ 570 MLGERLFPLI 580 QAMHPSLAGK 590 ITGMLLEIDN 600 SELLHMLESP 610 ESLRSKVDEA 620 VAVLQAHQAK 630 EAAQKAVNSA TGVPTV

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0010494	cytoplasmic stress granule
Cellular Component	GO:0030027	lamellipodium
Cellular Component	GO:0005681	spliceosomal complex
Molecular Function	GO:0003723	RNA binding
Biological Process	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
Biological Process	GO:0008380	RNA splicing

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.