Search Results
Overview
| Uniprot ID | A0A0G2JZT5 |
|---|---|
| Protein Name | Septin |
| Gene Name | Septin7 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 178 | EECQQFKKQIMKEIQ |
Function
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation
Protein Sequence
10
MVVDPPFSYL
20
SALTWTSSAI
30
VLCTCGESGL
40
GKSTLINSLF
50
LTDLYSPEYP
60
GPSHRIKKTV
70
QVEQSKVLIK
80
EGGVQLLLTI
90
VDTPGFGDAV
100
DNSNCWQPVI
110
DYIDSKFEDY
120
LNAESRVNRR
130
QMPDNRVQCC
140
LYFIAPSGHG
150
LKPLDIEFMK
160
RLHEKVNIIP
170
LIAKADTLTP
180
EECQQFKKQI
190
MKEIQEHKIK
200
IYEFPETDDE
210
EENKLVKKIK
220
DRLPLAVVGS
230
NTIIEVNGKR
240
VRGRQYPWGV
250
AEVENGEHCD
260
FTILRNMLIR
270
THMQDLKDVT
280
NNVHYENYRS
290
RKLAAVTYNG
300
VDNNKNKGQL
310
TKSPLAQMEE
320
ERREHVAKMK
330
KMEMEMEQVF
340
EMKVKEKVQK
350
LKDSEAELQR
360
RHEQMKKNLE
370
AQHKELEEKR
380
RQFEEEKANW
390
EAQQRILEQQ
400
NSSRTLEKNK
KKGKIF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0032154 | cleavage furrow |
| Cellular Component | GO:0005930 | axoneme |
| Cellular Component | GO:0000776 | kinetochore |
| Cellular Component | GO:0030496 | midbody |
| Cellular Component | GO:0031105 | septin complex |
| Cellular Component | GO:0005819 | spindle |
| Molecular Function | GO:0005525 | GTP binding |
| Biological Process | GO:0051301 | cell division |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.