Search Results
Overview
| Uniprot ID | A0A0G2K0D3 |
|---|---|
| Protein Name | Leiomodin-1 |
| Gene Name | Lmod1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 478 | QKRLQEQKQAQEASG |
| 501 | PKVGALPKGSPKPSP |
| 513 | PSPQPSPKSAPKNSP |
| 560 | TQRKMGDKVLPAQEK |
| 567 | KVLPAQEKNSRDQLL |
| 57 | RQRNQTDKQPSGSFN |
| 583 | AIRSSNLKQLKKVEV |
Function
Required for proper contractility of visceral smooth muscle cells (By similarity). Mediates nucleation of actin filaments (By similarity)
Protein Sequence
10
MSKVAKYRRQ
20
VSEDPDIDSL
30
LSTLSPEEME
40
ELEKELDVVD
50
PDGSIPVGLR
60
QRNQTDKQPS
70
GSFNREAMLN
80
FCEKESKKII
90
QREMSVDESK
100
QVGRKTDAKN
110
GEDKGSNASR
120
KALGPRQDSD
130
VGKEPKKGVL
140
KKSFSRDREE
150
ADSRGSEKPK
160
EEKVIRGIDK
170
GRVRAAVDRK
180
EAGKDGREER
190
AAATTKKEEE
200
KTGSVRNAGL
210
SRDKDKKREE
220
VKEPSKKEEV
230
KLTAENRSTV
240
GRQEDGKQKE
250
SREDRDKKPE
260
VKGIGCGSRD
270
SRKEDEKVKK
280
EETQPDKGVR
290
EEGKTREKQP
300
PSGPSKPSDG
310
QARAEEEAAP
320
SIFDEPLEKV
330
KNNDPEMTEV
340
NVNNSDCITN
350
EILVRFTEAL
360
EFNTVVKVFA
370
LANTRADDHV
380
AFAIAIMLKA
390
NKTITSLNLD
400
SNHITGKGIL
410
AIFRALLQNN
420
TLTELRFHNQ
430
RHICGGKTEM
440
EIAKLLKENT
450
TLLKLGYHFE
460
LAGPRMTVTN
470
LLSRNMDKQR
480
QKRLQEQKQA
490
QEASGEKKDR
500
LEVPKVGALP
510
KGSPKPSPQP
520
SPKSAPKNSP
530
KKAGVPAAPP
540
PPPPPLAPPL
550
IMENLKNSLS
560
PATQRKMGDK
570
VLPAQEKNSR
580
DQLLAAIRSS
590
NLKQLKKVEV
PKLLQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005884 | actin filament |
| Cellular Component | GO:0030017 | sarcomere |
| Cellular Component | GO:0005865 | striated muscle thin filament |
| Molecular Function | GO:0003779 | actin binding |
| Molecular Function | GO:0005523 | tropomyosin binding |
| Biological Process | GO:0007015 | actin filament organization |
| Biological Process | GO:0045010 | actin nucleation |
| Biological Process | GO:0006936 | muscle contraction |
| Biological Process | GO:0030239 | myofibril assembly |
| Biological Process | GO:0051694 | pointed-end actin filament capping |
| Biological Process | GO:0030838 | positive regulation of actin filament polymerization |
| Cellular Component | GO:0005856 | cytoskeleton |
| Cellular Component | GO:0030016 | myofibril |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.