Search Results

Overview

Uniprot IDA0A0G2K0T6
Protein NameGamma-synuclein
Gene NameSncg
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
21 GVVGAVEKTKQGVTE
23 VGAVEKTKQGVTEAA
32 GVTEAAEKTKEGVMY
34 TEAAEKTKEGVMYVG

Function

Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway

Protein Sequence

10 MDVFKKGFSI 20 AREGVVGAVE 30 KTKQGVTEAA 40 EKTKEGVMYV 50 GSSGEGQGVQ 60 PESSAVAEKT 70 KEQANAVSEA 80 VVSSVNTVAT 90 KTVEEAENIV 100 VTTGVVRKED 110 LEPPAQDQEA 120 KEQEEGEEAK SGGD

Gene Ontology

No Gene Ontology data available.

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.