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Overview

Uniprot ID	A0A0G2K2L0
Protein Name	DNA mismatch repair protein MLH1
Gene Name	Mlh1
Organism	Rattus norvegicus

Kla Sites from experimental identification

Position	Flanking peptide
130	TTKTADGKCAYRASY

Function

No function data available.

Protein Sequence

10 MAKSGANMAF 20 VAGVIRRLDE 30 TVVNRIAAGE 40 VIQRPANAIK 50 EMIENCLDAK 60 STNIQVIVKE 70 GGLKLIQIQD 80 NGTGIRKEDL 90 DIVCERFTTS 100 KLQTFEDLAS 110 ISTYGFRGEA 120 LASISHVAHV 130 TITTKTADGK 140 CAYRASYSDG 150 KLQAPPKPCA 160 GNQGTLITVE 170 DLFYNIITRR 180 KALKNPSEEY 190 GKILEVVGRY 200 SIHNSGISFS 210 VKKQGETVSD 220 VRTLPNATTV 230 DNIRSIFGNA 240 VSRELIEVGC 250 EDKTLAFKMN 260 GYISNANYSV 270 KKCIFLLFIN 280 HRLVESAALK 290 KAIEAVYAAY 300 LPKNTHPFLY 310 LSLEISPQNV 320 DVNVHPTKHE 330 VHFLHEESIL 340 ERVQQHIESK 350 LLGSNSSRMY 360 FTQTLLPGLA 370 GPSGEAVKST 380 TGIASSSTSG 390 SGDKVHAYQM 400 VRTDSRDQKL 410 DAFMQPVSRR 420 LPSQPQDPVP 430 GNRTEGSPEK 440 AMQKDQEMSE 450 LPAAMEAAAD 460 SASLERESVI 470 GASEVAPPAA 480 PPSSPGSSRK 490 RHREDSDEEM 500 MENDSRKEMT 510 AACYPRRRII 520 NLTSVLSLQE 530 EINDRGHETL 540 REMLRNHTFV 550 GCVNPQWALA 560 QHQTKLYLLN 570 TTKLSEELFY 580 QILIYDFANF 590 GVLRLSEPAP 600 LFDLAMLALD 610 SPESGWTEED 620 GPKEGLAEYI 630 VEFLKKKAEM 640 LADYFSVEID 650 EEGNLIGLPL 660 LIDSYVPPLE 670 GLPIFILRLA 680 TEVNWDEEKE 690 CFESLSKECA 700 VFYSIRKQYI 710 LEESALSGQQ 720 SDMPGSPSKP 730 WKWTVEHIIY 740 KAFRSHLLPP 750 KHFTEDGNVL 760 QLANLPDLYK VFERC

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0032300	mismatch repair complex
Cellular Component	GO:0000795	synaptonemal complex
Molecular Function	GO:0005524	ATP binding
Molecular Function	GO:0016887	ATP hydrolysis activity
Molecular Function	GO:0140664	ATP-dependent DNA damage sensor activity
Molecular Function	GO:0030983	mismatched DNA binding
Biological Process	GO:0006298	mismatch repair

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.