Search Results
Overview
| Uniprot ID | A0A0G2K472 |
|---|---|
| Protein Name | Cytoplasmic FMR1-interacting protein |
| Gene Name | Cyfip1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 540 | LRGEKDPKSGFDIKV |
Function
No function data available.
Protein Sequence
10
MAAQVTLEDA
20
LSNVDLLEEL
30
PLPDQQPCIE
40
PPPSSLLYQP
50
NFNTNFEDRN
60
AFVTGIARYI
70
EQATVHSSMN
80
EMLEEGQEYA
90
VMLYTWRSCS
100
RAIPQVKCNE
110
QPNRVEIYEK
120
TVEVLEPEVT
130
KLMNFMYFQR
140
NAIERFCGEV
150
RRLCHAERRK
160
DFVSEAYLIT
170
LGKFINMFAV
180
LDELKNMKCS
190
VKNDHSAYKR
200
AAQFLRKMAD
210
PQSIQESQNL
220
SMFLANHNKI
230
TQSLQQQLEV
240
ISGYEELLAD
250
IVNLCVDYYE
260
NRMYLTPSEK
270
HMLLKVMGFG
280
LYLMDGSVSN
290
IYKLDAKKRI
300
NLSKIDKYFK
310
QLQVVPLFGD
320
MQIELARYIK
330
TSAHYEENKS
340
RWTCTSSSSS
350
PQYNICEQMI
360
QIREDHMRFI
370
SELARYSNSE
380
VVTGSGRQEA
390
QKTDAEYRKL
400
FDLALQGLQL
410
LSQWSAHVME
420
VYSWKLVHPT
430
DKYSNKDCPD
440
NAEEYERATR
450
YNYTTEEKFA
460
LVEVIAMIKG
470
LQVLMGRMES
480
VFNHAIRHTV
490
YAALQDFSQV
500
TLREPLRQAI
510
KKKKNVIQSV
520
LQAIRKTVCD
530
WETGHEPFND
540
PALRGEKDPK
550
SGFDIKVPRR
560
AVGPSSTQLY
570
LVRTMAESLS
580
SAELLRQLKS
590
LGMERLLHVV
600
NAFLRQSYTY
610
PPLLTFGETL
620
QQCCDLSQLW
630
FREFFLELTM
640
GRRIQFPIEM
650
SMPWILTDHI
660
LETKEASMME
670
YVLYSLDLYN
680
DSAHYALTKF
690
NKQFLYDEIE
700
AEVNLCFDQF
710
VYKLADQIFA
720
YYKVMAGSLL
730
LDKRLRSECK
740
NQGATIHLPP
750
SNRYETLLKQ
760
RHVQLLGRSI
770
DLNRLITQRV
780
SAAMYKSLEL
790
AIGRFESEDL
800
TSVVELDGLL
810
EINRMTHKLL
820
SRYLTLDSFD
830
AMFREANHNV
840
SAPYGRITLH
850
VFWELNYDFL
860
PNYCYNGSTN
870
RFVRTVLPFS
880
QEFQRDKQPN
890
AQPQYLHGSK
900
ALNLAYSSIY
910
GSYRNFVGPP
920
HFQVICRLLG
930
YQGIAVVMEE
940
LLKVVKSLLQ
950
GTILQYVKTL
960
MEVMPKICRL
970
PRHEYGSPGI
980
LEFFHHQLKD
990
IVEYAELKTV
1000
CFQNLREVGN
1010
AVLFCLLIEQ
1020
SLSLEEVCDL
1030
LHAAPFQNIL
1040
PRVHVKEGER
1050
VDAKMKRLES
1060
KYAPLHLVPL
1070
IERLGTPQQI
1080
AIAREGDLLT
1090
KERLCCGLSM
1100
FEVILTRIRT
1110
FLDDPIWRGP
1120
LPSNGVMHVD
1130
ECVEFHRLWS
1140
AMQFVYCIPV
1150
GTHEFTVEQC
1160
FGDGLHWAGC
1170
MIIVLLGQQR
1180
RFAVLDFCYH
1190
LLKVQKHDGK
1200
DEIIKNVPLK
1210
KMVERIRKFQ
1220
ILNDEIITIL
1230
DKYLKSGDGE
1240
STPVEHVRCF
1250
QPPIHQSLAS
S
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0044295 | axonal growth cone |
| Cellular Component | GO:0031252 | cell leading edge |
| Cellular Component | GO:0090724 | central region of growth cone |
| Cellular Component | GO:0044294 | dendritic growth cone |
| Cellular Component | GO:0043197 | dendritic spine |
| Cellular Component | GO:0060076 | excitatory synapse |
| Cellular Component | GO:0032433 | filopodium tip |
| Cellular Component | GO:0030027 | lamellipodium |
| Cellular Component | GO:0043005 | neuron projection |
| Cellular Component | GO:0043025 | neuronal cell body |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0090725 | peripheral region of growth cone |
| Cellular Component | GO:0098794 | postsynapse |
| Cellular Component | GO:0031209 | SCAR complex |
| Cellular Component | GO:0043195 | terminal bouton |
| Cellular Component | GO:1903502 | translation repressor complex |
| Molecular Function | GO:0000340 | RNA 7-methylguanosine cap binding |
| Molecular Function | GO:0031267 | small GTPase binding |
| Molecular Function | GO:0030371 | translation repressor activity |
| Biological Process | GO:0048675 | axon extension |
| Biological Process | GO:0032869 | cellular response to insulin stimulus |
| Biological Process | GO:0050890 | cognition |
| Biological Process | GO:0097484 | dendrite extension |
| Biological Process | GO:0030032 | lamellipodium assembly |
| Biological Process | GO:1903422 | negative regulation of synaptic vesicle recycling |
| Biological Process | GO:0031175 | neuron projection development |
| Biological Process | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation |
| Biological Process | GO:0045773 | positive regulation of axon extension |
| Biological Process | GO:0050772 | positive regulation of axonogenesis |
| Biological Process | GO:1900006 | positive regulation of dendrite development |
| Biological Process | GO:0010592 | positive regulation of lamellipodium assembly |
| Biological Process | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway |
| Biological Process | GO:1900029 | positive regulation of ruffle assembly |
| Biological Process | GO:0016601 | Rac protein signal transduction |
| Biological Process | GO:0030833 | regulation of actin filament polymerization |
| Biological Process | GO:1905274 | regulation of modification of postsynaptic actin cytoskeleton |
| Biological Process | GO:0031641 | regulation of myelination |
| Biological Process | GO:0099578 | regulation of translation at postsynapse, modulating synaptic transmission |
| Biological Process | GO:0051602 | response to electrical stimulus |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.
[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.