Search Results
Overview
| Uniprot ID | A0A0G2K585 |
|---|---|
| Protein Name | Actin-related protein 2/3 complex subunit 5 |
| Gene Name | Arpc5 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 13 | VSSARFRKVDVDEYD |
| 3 | *****MSKNTVSSAR |
| 67 | KNPPINTKSQAVKAL |
Function
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development
Protein Sequence
10
MSKNTVSSAR
20
FRKVDVDEYD
30
ENKFVDEEDG
40
GDGQAGPDEG
50
EVDSCLRQGN
60
MTAALQAALK
70
NPPINTKSQA
80
VKALAAGGVG
90
SIVRVLTARK
TV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005885 | Arp2/3 protein complex |
| Biological Process | GO:0034314 | Arp2/3 complex-mediated actin nucleation |
| Biological Process | GO:0030833 | regulation of actin filament polymerization |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.