Search Results

Overview

Uniprot ID	A0A0G2K5Q2
Protein Name	Crooked neck-like protein 1
Gene Name	Crnkl1
Organism	Rattus norvegicus

Kla Sites from experimental identification

Position	Flanking peptide
21	KVAKVKNKAPAEVQI
9	AASTAAGKQRIPKVA

Function

Involved in pre-mRNA splicing process. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs

Protein Sequence

10 MAASTAAGKQ 20 RIPKVAKVKN 30 KAPAEVQITA 40 EQLLREAKER 50 ELELLPPPPQ 60 QKITDEEELN 70 DYKLRKRKTF 80 EDNIRKNRTV 90 ISNWIKYAQW 100 EESLKEIQRA 110 RSIYERALDV 120 DYRNITLWLK 130 YAEMEMKNRQ 140 VNHARNIWDR 150 AITTLPRVNQ 160 FWYKYTYMEE 170 MLGNVAGARQ 180 VFEHWMEWQP 190 EEQAWHSYIN 200 FELRYKEVER 210 ARTIYERFVL 220 VHPAVKNWIK 230 YARFEEKHAY 240 FAHARKVYER 250 AVEFFGDEHM 260 DEHLYVAFAK 270 FEENQKEFER 280 VRVIYKYALD 290 RISKQEAQEL 300 FKNYTIFEKK 310 FGDRRGIEDI 320 IVSKRRFQYE 330 EEVKANPHNY 340 DAWFDYLRLV 350 ESDAEADTVR 360 EVYERAIANV 370 PPIQEKRHWK 380 RYIYLWVNYA 390 LYEELEAKDP 400 ERTRQVYQAS 410 LELIPHKKFT 420 FAKMWLYYAQ 430 FEIRQKNLPF 440 ARRALGTSIG 450 KCPKNKLFKG 460 YIELELQLRE 470 FDRCRKLYEK 480 FLEFEPENCT 490 SWIKFAELET 500 ILGDIERARA 510 IYELAISQPR 520 LDMPEVLWKS 530 YIDFEIEQEE 540 TERTRNLYRQ 550 LLQRTQHVKV 560 WISFAQFELS 570 SVKEGSVAKC 580 RQIYEEANKT 590 MRNCEEKEER 600 LMLLESWRSF 610 EDEFGTVSDK 620 ERVDKLMPEK 630 VKKRRKVQAD 640 DGSDAGWEEY 650 YDYIFPEDAA 660 NQPNLKLLAM 670 AKLWKKQQQE 680 REAAEQDPDK 690 DIDESESSSF

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0016607	nuclear speck
Cellular Component	GO:0005681	spliceosomal complex
Biological Process	GO:0000398	mRNA splicing, via spliceosome

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.