Search Results
Overview
| Uniprot ID | A0A0G2K6I4 |
|---|---|
| Protein Name | Protein enabled homolog |
| Gene Name | Enah |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 454 | RRRRIAEKGSTIETE |
Function
Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation
Protein Sequence
10
MDVEFVSYSI
20
PKLRSSQSLR
30
ISEQSICQAR
40
AAVMVYDDAN
50
KKWVPAGGST
60
GFSRVHIYHH
70
TGNNTFRVVG
80
RKIQDHQVVI
90
NCAIPKGLKY
100
NQATQTFHQW
110
RDARQVYGLN
120
FGSKEDANVF
130
ASAMMHALEV
140
LNSQEAGPTL
150
PRQNSQLPAQ
160
VQNGPSQEEM
170
EIQRRQLQEQ
180
QRQKELERER
190
MERERLERER
200
LERERLERER
210
LEQEQLERQR
220
QEREHVERLE
230
RERLERLERE
240
RQDRERERER
250
LEQLEREQVE
260
WERERRMSNA
270
AAPASVETPL
280
NPELGDSSAS
290
EPGLQAASQP
300
AETPAPQGHV
310
LGPPAPPPPP
320
PLPSGPAYAS
330
ALPPPPGPPP
340
PPPLPSAGPP
350
PPPPPPPPLP
360
NQVPPPPPPP
370
PAPPLPASGI
380
FSGSMSEDNR
390
PLTGLAAAIA
400
GAKLRKVSRV
410
EDGSFPSGGN
420
TVSVNLASSK
430
TDSGRGNGPL
440
PLGGSGLMEE
450
MSALLARRRR
460
IAEKGSTIET
470
EQKEDRSEDA
480
EPVTSKAAST
490
STPEPTRKPW
500
ERTNTMNGSK
510
SPVISRPKST
520
PSSQPSANGV
530
QTEGLDYDRL
540
KQDILDEMRK
550
ELAKLKEELI
560
DAIRQELSKS
NTA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005856 | cytoskeleton |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0030175 | filopodium |
| Cellular Component | GO:0005925 | focal adhesion |
| Cellular Component | GO:0030027 | lamellipodium |
| Cellular Component | GO:0045202 | synapse |
| Molecular Function | GO:0003779 | actin binding |
| Molecular Function | GO:0017124 | SH3 domain binding |
| Biological Process | GO:0001843 | neural tube closure |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.