Search Results
Overview
| Uniprot ID | A0A0H2UHP0 |
|---|---|
| Protein Name | Transcriptional repressor CTCF |
| Gene Name | Ctcf |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 202 | PDYQPPAKKTKKTKK |
| 264 | IKKKGVKKTFQCELC |
Function
No function data available.
Protein Sequence
10
MEGEAVEAIV
20
EESETFIKGK
30
ERKTYQRRRE
40
GGQEEDACHL
50
PQNQTDGGEV
60
VQDVNSSVQM
70
VMMEQLDPTL
80
LQMKTEVMEG
90
TVAPEAEAAV
100
DDTQIITLQV
110
VNMEEQPINI
120
GELQLVQVPV
130
PVTVPVATTS
140
VEELQGAYEN
150
EVSKEGLAES
160
EPMICHTLPL
170
PEGFQVVKVG
180
ANGEVETLEQ
190
GELPPQEDPS
200
WQKDPDYQPP
210
AKKTKKTKKS
220
KLRYTEEGKD
230
VDVSVYDFEE
240
EQQEGLLSEV
250
NAEKVVGNMK
260
PPKPTKIKKK
270
GVKKTFQCEL
280
CSYTCPRRSN
290
LDRHMKSHTD
300
ERPHKCHLCG
310
RAFRTVTLLR
320
NHLNTHTGTR
330
PHKCPDCDMA
340
FVTSGELVRH
350
RRYKHTHEKP
360
FKCSMCDYAS
370
VEVSKLKRHI
380
RSHTGERPFQ
390
CSLCSYASRD
400
TYKLKRHMRT
410
HSGEKPYECY
420
ICHARFTQSG
430
TMKMHILQKH
440
TENVAKFHCP
450
HCDTVIARKS
460
DLGVHLRKQH
470
SYIEQGKKCR
480
YCDAVFHERY
490
ALIQHQKSHK
500
NEKRFKCDQC
510
DYACRQERHM
520
IMHKRTHTGE
530
KPYACSHCDK
540
TFRQKQLLDM
550
HFKRYHDPNF
560
VPAAFVCSKC
570
GKTFTRRNTM
580
ARHADNCAGP
590
DGVEGENGGE
600
TKKSKRGRKR
610
KMRSKKEDSS
620
DSEENAEPDL
630
DDNEEEEEPA
640
VEIEPEPEPQ
650
PQPQPQPQPQ
660
PVAPAPPPAK
670
KRRGRPPGRT
680
NQPKQNQPTA
690
IIQVEDQNTG
700
AIENIIVEVK
710
KEPDAEPAEG
720
EEEEAQAAPA
730
DAPNGDLTPE
MILSMMDR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000775 | chromosome, centromeric region |
| Cellular Component | GO:0000793 | condensed chromosome |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005654 | nucleoplasm |
| Molecular Function | GO:0043035 | chromatin insulator sequence binding |
| Molecular Function | GO:0140587 | chromatin loop anchoring activity |
| Molecular Function | GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| Molecular Function | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| Molecular Function | GO:0001221 | transcription coregulator binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0140588 | chromatin looping |
| Biological Process | GO:0007059 | chromosome segregation |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0071514 | genomic imprinting |
| Biological Process | GO:0008285 | negative regulation of cell population proliferation |
| Biological Process | GO:0010629 | negative regulation of gene expression |
| Biological Process | GO:0010628 | positive regulation of gene expression |
| Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| Biological Process | GO:0071459 | protein localization to chromosome, centromeric region |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.