Search Results
Overview
| Uniprot ID | A0A0H2UHZ4 |
|---|---|
| Protein Name | Zinc finger Ran-binding domain-containing protein 2 |
| Gene Name | Zranb2 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 137 | KKKKYRGKAVGPASI |
| 18 | GDWICPDKKCGNVNF |
| 43 | REKTTEAKMMKAGGT |
| 46 | TTEAKMMKAGGTEIG |
| 54 | AGGTEIGKTLAEKSR |
| 92 | CNMCNTPKYAKLEER |
| 95 | CNTPKYAKLEERTGY |
Function
Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3'. May interfere with constitutive 5'-splice site selection
Protein Sequence
10
MSTKNFRVSD
20
GDWICPDKKC
30
GNVNFARRTS
40
CNRCGREKTT
50
EAKMMKAGGT
60
EIGKTLAEKS
70
RGLFSANDWQ
80
CKTCSNVNWA
90
RRSECNMCNT
100
PKYAKLEERT
110
GYGGGFNERE
120
NVEYIEREES
130
DGEYDEFGRK
140
KKKYRGKAVG
150
PASILKEVED
160
KESEGEEEDE
170
DEDLSKYKLD
180
EDEDEDDADL
190
SKYNLDASEE
200
EDSNKKKSNR
210
RSRSKSRSSH
220
SRSSSRSSSP
230
SSSRSRSRSR
240
SRSSSSSQSR
250
SHSGSREHSR
260
SRGSKSRSSS
270
RSHRGSSSPR
280
KRSYSSSSSS
290
PERDRKRSRS
300
RPSSPAVRKK
310
RRTRSRSPES
320
QVIGENIKQP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0006396 | RNA processing |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.
[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.