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Overview

Uniprot IDA0A0R0HEQ3
Protein NameHistone H2B
Gene NameLOC100778668
OrganismGlycine max

Kla Sites from experimental identification

Position Flanking peptide
110 SRLARYNKKPTITSR
25 KKSTVGDKAPAEKKP

Function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling

Protein Sequence

10 MAPKAEKKPA 20 EKKPAEEKKS 30 TVGDKAPAEK 40 KPKAGKKLPK 50 EGGAGGEGGK 60 KKKRNKKSVE 70 TYKIYIFKVL 80 KQVHPDIGIS 90 SKAMGIMNSF 100 INDIFEKLAQ 110 ESSRLARYNK 120 KPTITSREIQ 130 TAVRLVLPGE 140 LAKHAVSEGT KAVTKFTSS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0000786 nucleosome
Cellular Component GO:0005634 nucleus
Molecular Function GO:0003677 DNA binding
Molecular Function GO:0046982 protein heterodimerization activity
Molecular Function GO:0030527 structural constituent of chromatin
Biological Process GO:0006325 chromatin organization

Reference

[1] Xu C, Li J, Dong C, Zhang Y, Li H et al.. Lactylome Profiling Reveals the Potential Role of Lysine Lactylation in Regulating Soybean Seed Quality.. J Agric Food Chem 73(23):14666-14676. 2025 Jun 11. PMID: 40440508.