Search Results
Overview
| Uniprot ID | A0A0S2Z3X8 |
|---|---|
| Protein Name | Rab GDP dissociation inhibitor |
| Gene Name | GDI1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 309 | CILSHPIKNTNDANS |
Function
Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP
Protein Sequence
10
MDEEYDVIVL
20
GTGLTECILS
30
GIMSVNGKKV
40
LHMDRNPYYG
50
GESSSITPLE
60
ELYKRFQLLE
70
GPPESMGRGR
80
DWNVDLIPKF
90
LMANGQLVKM
100
LLYTEVTRYL
110
DFKVVEGSFV
120
YKGGKIYKVP
130
STETEALASN
140
LMGMFEKRRF
150
RKFLVFVANF
160
DENDPKTFEG
170
VDPQTTSMRD
180
VYRKFDLGQD
190
VIDFTGHALA
200
LYRTDDYLDQ
210
PCLETVNRIK
220
LYSESLARYG
230
KSPYLYPLYG
240
LGELPQGFAR
250
LSAIYGGTYM
260
LNKPVDDIIM
270
ENGKVVGVKS
280
EGEVARCKQL
290
ICDPSYIPDR
300
VRKAGQVIRI
310
ICILSHPIKN
320
TNDANSCQII
330
IPQNQVNRKS
340
DIYVCMISYA
350
HNVAAQGKYI
360
AIASTTVETT
370
DPEKEVEPAL
380
ELLEPIDQKF
390
VAISDLYEPI
400
DDGCESQVFC
410
SCSYDATTHF
420
ETTCNDIKDI
430
YKRMAGTAFD
440
FENMKRKQND
VFGEAEQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030424 | axon |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0043209 | myelin sheath |
| Cellular Component | GO:0043025 | neuronal cell body |
| Cellular Component | GO:0099523 | presynaptic cytosol |
| Cellular Component | GO:0032991 | protein-containing complex |
| Molecular Function | GO:0005096 | GTPase activator activity |
| Molecular Function | GO:0005093 | Rab GDP-dissociation inhibitor activity |
| Molecular Function | GO:0031267 | small GTPase binding |
| Biological Process | GO:0050771 | negative regulation of axonogenesis |
| Biological Process | GO:0045773 | positive regulation of axon extension |
| Biological Process | GO:0015031 | protein transport |
| Biological Process | GO:0032880 | regulation of protein localization |
| Biological Process | GO:0051592 | response to calcium ion |
| Biological Process | GO:0007264 | small GTPase-mediated signal transduction |
Reference
PMID: N/A