Search Results
Overview
| Uniprot ID | A0A0U1RS25 |
|---|---|
| Protein Name | Regulator of nonsense transcripts 1 |
| Gene Name | Upf1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 924 | MQFSKPRKLVNTVNP |
Function
No function data available.
Protein Sequence
10
MSVEAYGPSS
20
QTLTFLDTEE
30
AELLGADTQG
40
SEFEFTDFTL
50
PSQTQTPPGG
60
PGGAGGPGGA
70
GAGGAAGQLD
80
AQVGPEGILQ
90
NGAVDDSVAK
100
TSQLLAELNF
110
EEDEEDTYYT
120
KDLPVHACSY
130
CGIHDPACVV
140
YCNTSKKWFC
150
NGRGNTSGSH
160
IVNHLVRAKC
170
KEVTLHKDGP
180
LGETVLECYN
190
CGCRNVFLLG
200
FIPAKADSVV
210
VLLCRQPCAS
220
QSSLKDINWD
230
SSQWQPLIQD
240
RCFLSWLVKI
250
PSEQEQLRAR
260
QITAQQINKL
270
EELWKENPSA
280
TLEDLEKPGV
290
DEEPQHVLLR
300
YEDAYQYQNI
310
FGPLVKLEAD
320
YDKKLKESQT
330
QDNITVRWDL
340
GLNKKRIAFF
350
TLPKTDSGNE
360
DLVIIWLRDM
370
RLMQGDEICL
380
RYKGDLAPLW
390
KGIGHVIKVP
400
DNYGDEIAIE
410
LRSSVGAPVE
420
VTHNFQVDFV
430
WKSTSFDRMQ
440
SALKTFAVDE
450
TSVSGYIYHK
460
LLGHEVEDVV
470
IKCQLPKRFT
480
AQGLPDLNHS
490
QVYAVKTVLQ
500
RPLSLIQGPP
510
GTGKTVTSAT
520
IVYHLARQGN
530
GPVLVCAPSN
540
IAVDQLTEKI
550
HQTGLKVVRL
560
CAKSREAIDS
570
PVSFLALHNQ
580
IRNMDSMPEL
590
QKLQQLKDET
600
GELSSADEKR
610
YRALKRTAER
620
ELLMNADVIC
630
CTCVGAGDPR
640
LAKMQFRSIL
650
IDESTQATEP
660
ECMVPVVLGA
670
KQLILVGDHC
680
QLGPVVMCKK
690
AAKAGLSQSL
700
FERLVVLGIR
710
PIRLQVQYRM
720
HPALSAFPSN
730
IFYEGSLQNG
740
VTAADRVKKG
750
FDFQWPQPDK
760
PMFFYVTQGQ
770
EEIASSGTSY
780
LNRTEAANVE
790
KITTKLLKAG
800
AKPDQIGIIT
810
PYEGQRSYLV
820
QYMQFSGSLH
830
TKLYQEVEIA
840
SVDAFQGREK
850
DFIILSCVRA
860
NEHQGIGFLN
870
DPRRLNVALT
880
RARYGVIIVG
890
NPKALSKQPL
900
WNHLLSYYKE
910
QKALVEGPLN
920
NLRESLMQFS
930
KPRKLVNTVN
940
PGARFMTTAM
950
YDAREAIIPG
960
SVYDRSSQGR
970
PSNMYFQTHD
980
QISMISAGPS
990
HVAAMNIPIP
1000
FNLVMPPMPP
1010
PGYFGQANGP
1020
AAGRGTPKSK
1030
TGRGGRQKNR
1040
FGLPGPSQTT
1050
LPNSQASQDV
1060
ASQPFSQGAL
1070
TQGYVSMSQP
1080
SQMSQPGLSQ
1090
PELSQDSYLG
1100
DEFKSQIDVA
1110
LSQDSTYQGE
1120
RAYQHGGVTG
LSQY
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000785 | chromatin |
| Molecular Function | GO:0003724 | RNA helicase activity |
| Molecular Function | GO:0042162 | telomeric DNA binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0061158 | 3'-UTR-mediated mRNA destabilization |
| Biological Process | GO:0044770 | cell cycle phase transition |
| Biological Process | GO:0006281 | DNA repair |
| Biological Process | GO:0006260 | DNA replication |
| Biological Process | GO:0071044 | histone mRNA catabolic process |
| Biological Process | GO:0000956 | nuclear-transcribed mRNA catabolic process |
| Biological Process | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| Biological Process | GO:0061014 | positive regulation of mRNA catabolic process |
| Biological Process | GO:1905746 | positive regulation of mRNA cis splicing, via spliceosome |
| Biological Process | GO:0032204 | regulation of telomere maintenance |
| Biological Process | GO:0006449 | regulation of translational termination |
| Biological Process | GO:0032201 | telomere maintenance via semi-conservative replication |
| Cellular Component | GO:0000781 | chromosome, telomeric region |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0036464 | cytoplasmic ribonucleoprotein granule |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0035145 | exon-exon junction complex |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0044530 | supraspliceosomal complex |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016887 | ATP hydrolysis activity |
| Molecular Function | GO:0003682 | chromatin binding |
| Molecular Function | GO:0036121 | double-stranded DNA helicase activity |
| Molecular Function | GO:0044877 | protein-containing complex binding |
| Molecular Function | GO:0003723 | RNA binding |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.