Search Results
Overview
| Uniprot ID | A0A286X7D3 |
|---|---|
| Protein Name | PC4 and SFRS1-interacting protein |
| Gene Name | PSIP1 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 143 | AVDITTPKAARRGRK |
| 16 | DLIFAKMKGYPHWPA |
| 188 | RPAASDVKIPKPRGR |
| 200 | RGRPKMVKQPCPSES |
| 303 | AHRRNMLKSQHEKEA |
| 332 | QQNKDEGKKPEVKKV |
| 400 | TEMITTLKKIRRFKV |
| 406 | LKKIRRFKVSQVIME |
| 91 | IDNNPKVKFSSQQVS |
Function
Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis
Protein Sequence
10
MTRDFKPGDL
20
IFAKMKGYPH
30
WPARVDEVPD
40
GAVKPPTNKL
50
PIFFFGTHET
60
AFLGPKDIFP
70
YSENKEKYGK
80
PNKRKGFNEG
90
LWEIDNNPKV
100
KFSSQQVSTK
110
QSNASSDVEV
120
EEKETSVSKE
130
DSDHEEKTSS
140
EDMTKAVDIT
150
TPKAARRGRK
160
RKAEKVETEE
170
AGVVTTATAS
180
VNLKVSPKRG
190
RPAASDVKIP
200
KPRGRPKMVK
210
QPCPSESDMV
220
AEDDKSKKKG
230
QEEKQPKKQP
240
KKDEEGQKEE
250
DKPRKEPDKK
260
EGKKEIESKR
270
KNLAKTGVTS
280
TSDSEEEGDD
290
QEGEKKRKGG
300
RNLQTAHRRN
310
MLKSQHEKEA
320
ADRKRKQEEQ
330
METEQQNKDE
340
GKKPEVKKVE
350
KKRETSMDSR
360
LQRIHAEIKN
370
SLKIDNLDVN
380
RCIEALDELA
390
SLQVTMQQAQ
400
KHTEMITTLK
410
KIRRFKVSQV
420
IMEKSTMLYN
430
KFKNMFLVGE
440
GDSVITQVLN
450
KSLAEQRQHE
460
EANKTKDQGK
470
KGPNKKLEKE
480
QTGSKTLNGG
490
SDAQDSNQPQ
500
HNGDSNEESK
510
DNHEAGSKKK
520
PSSEERETEV
SLKESTVDN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005654 | nucleoplasm |
| Molecular Function | GO:0003677 | DNA binding |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0000395 | mRNA 5'-splice site recognition |
| Biological Process | GO:0009408 | response to heat |
| Biological Process | GO:0006979 | response to oxidative stress |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.