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Overview

Uniprot IDA0A286XCD7
Protein NamePDZ and LIM domain protein 3
Gene NamePDLIM3
OrganismCavia porcellus

Kla Sites from experimental identification

Position Flanking peptide
230 SVRAPVTKVHGGAGG

Function

May play a role in the organization of actin filament arrays within muscle cells

Protein Sequence

10 MPQTVVLPGP 20 APWGFRLSGG 30 IDFNQPLVIT 40 RITPGSKAAA 50 ANLCPGDVIL 60 AIDGFGTESM 70 THADAQDRIK 80 AAAHQLCLKI 90 DRAETRLWSP 100 QVSEDGKAHP 110 FKINLESEPQ 120 EFRPIGTAHN 130 RRAQPFVAAA 140 NIDDKRQVVS 150 ASYNSPIGLY 160 STSNIQDALH 170 GQLRGLLPSS 180 PQNEPVASVP 190 PQSDVYRMLH 200 DNRDEPTQPR 210 QSGSFRVLQE 220 LVNDDDRPAG 230 TRSVRAPVTK 240 VHGGAGGAQR 250 MPLCDKCGSG 260 IVGAVVKARD 270 KYRHPECFVC 280 ADCNLNLKQK 290 GYFFVEGELY 300 CETHARARTR 310 PPEGYDTVTL YPKA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005912 adherens junction
Cellular Component GO:0031941 filamentous actin
Cellular Component GO:0001725 stress fiber
Cellular Component GO:0030018 Z disc
Molecular Function GO:0003779 actin binding
Molecular Function GO:0046872 metal ion binding
Molecular Function GO:0051371 muscle alpha-actinin binding
Biological Process GO:0030036 actin cytoskeleton organization
Biological Process GO:0007507 heart development
Biological Process GO:0061061 muscle structure development

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.