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Overview

Uniprot IDA0A286XEP9
Protein NameClathrin light chain
Gene NameCLTA
OrganismCavia porcellus

Kla Sites from experimental identification

Position Flanking peptide
205 RLCDFNPKSSKQAKD
224 RSVLISLKQAPLVH*

Function

Clathrin is the major protein of the polyhedral coat of coated pits and vesicles

Protein Sequence

10 MAELDPFGAP 20 AGSALGNGVA 30 GEEDPAAAFL 40 AQQESEIAGI 50 ENDEAFAILD 60 GGAPGPQPHG 70 EPPGGPDAVD 80 GVMNGEYYQE 90 SNGPTDSYAA 100 VSQVDRLQSE 110 PESIRKWREE 120 QTERLEALDA 130 NSRKQEAEWK 140 EKAIKELEEW 150 YARQDEQLQK 160 TKANNRVADE 170 AFYRQPFADV 180 IGYVAAEEAF 190 VNDIDESSPG 200 TEWERVARLC 210 DFNPKSSKQA 220 KDVSRMRSVL 230 ISLKQAPLVH

Gene Ontology

Classification GO ID Description
Cellular Component GO:0030132 clathrin coat of coated pit
Cellular Component GO:0030130 clathrin coat of trans-Golgi network vesicle
Cellular Component GO:0099631 postsynaptic endocytic zone cytoplasmic component
Cellular Component GO:0030672 synaptic vesicle membrane
Molecular Function GO:0032050 clathrin heavy chain binding
Molecular Function GO:0005198 structural molecule activity
Biological Process GO:0072583 clathrin-dependent endocytosis
Biological Process GO:0006886 intracellular protein transport

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.