Search Results
Overview
| Uniprot ID | A0A286XIM5 |
|---|---|
| Protein Name | Nuclear factor 1 |
| Gene Name | NFIX |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 249 | PPSTSTTKRPKSIDD |
Function
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication
Protein Sequence
10
MGDEFHPFIE
20
ALLPHVRAFS
30
YTWFNLQARK
40
RKYFKKHEKR
50
MSKDEERAVK
60
DELLGEKPEI
70
KQKWASRLLA
80
KLRKDIRPEF
90
REDFVLTITG
100
KKPPCCVLSN
110
PDQKGKIRRI
120
DCLRQADKVW
130
RLDLVMVILF
140
KGIPLESTDG
150
ERLYKSPQCS
160
NPGLCVQPHH
170
IGVTIKELDL
180
YLAYFVHTPE
190
SGQSDSSNQQ
200
GDADIKPLPN
210
GQLSQTPVAT
220
ASGPNFSLAD
230
LESPSYYNIN
240
QVTLGRRSIT
250
SPPSTSTTKR
260
PKSIDDSEME
270
SPVDDVFYPG
280
TGRSPAAGSS
290
QSSGWPNDVD
300
AGSPRATASA
310
LHFPSTSIIQ
320
QSSPYFTHPT
330
IRYHHHHGQD
340
SLKEFVQFVC
350
SDGSGQATGQ
360
VSVGATEPAT
370
PVSAPAVCLP
380
IHLGSWGAYC
390
IVLLWVQHGL
PSPSSCEP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Molecular Function | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| Biological Process | GO:0006260 | DNA replication |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0045893 | positive regulation of DNA-templated transcription |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.