Search Results
Overview
| Uniprot ID | A0A286XJI1 |
|---|---|
| Protein Name | Nuclear factor 1 |
| Gene Name | NFIA |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 267 | TSSTSSTKRLKSVED |
Function
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication
Protein Sequence
10
DEFHPFIEAL
20
LPHVRAFAYT
30
WFNLQARKRK
40
YFKKHEKRMS
50
KEEERAVKDE
60
LLSEKPEVKQ
70
KWASRLLAKL
80
RKDIRPEYRE
90
DFVLTVTGKK
100
PPCCVLSNPD
110
QKGKMRRIDC
120
LRQADKVWRL
130
DLVMVILFKG
140
IPLESTDGER
150
LVKSPQCSNP
160
GLCVQPHHIG
170
VSVKELDLYL
180
AYFVHAADSS
190
QSESPSQPSD
200
ADIKDQPENG
210
HLGFQDSFVT
220
SGVFSVTELV
230
RVSQTPIAAG
240
TGPNFSLSDL
250
ESSSYYSMSP
260
GAMRRSLPST
270
SSTSSTKRLK
280
SVEDEMDSPG
290
EEPFYTSQGR
300
SPGSGSQSSG
310
WHEVEPASPH
320
ATPSTLHFPT
330
SPIIQQPGPY
340
FSHPAIRYHP
350
QETLKEFVQL
360
VCPDAGQQAG
370
QVGFLNPNGS
380
SQGKVHNPFL
390
PTPMLPPPPP
400
PPMARPVPLP
410
VPDTKPPATS
420
TEGGAASPTS
430
PTYSTPSTSP
440
ANRFVSVGPR
450
DPSFVNIPQQ
TQSWYLG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Molecular Function | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| Biological Process | GO:0006260 | DNA replication |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0045893 | positive regulation of DNA-templated transcription |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.