Search Results

Overview

Uniprot ID	A0A286XLI3
Protein Name	RNA-binding protein 10
Gene Name	RBM10
Organism	Cavia porcellus

Kla Sites from experimental identification

Position	Flanking peptide
387	HGYLKGTKGPGITGT
577	KTAQQIAKDMERWAR
623	AGYAILEKKGALAER
761	PPEPKRRKYGGISTA
844	SYKETLHKTMVTRFN

Function

Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3'. May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A). May bind to specific miRNA hairpins

Protein Sequence

10 MTEFDSQGGR 20 GDRTGRYGAT 30 DRSQDDGGET 40 RSRDHDYRDM 50 DYRSYPREYG 60 SQEGKHDYDD 70 SSEEQSAEIR 80 GQLQSHGVQA 90 REVRLMRNKS 100 SGQSRGFAFV 110 EFSHLQDATR 120 WMEANQHSLN 130 ILGQKVSMHY 140 SDPKPKINED 150 WLCNKCGVQN 160 FKRREKCFKC 170 GVPKSEAEQK 180 LPLGARLDPQ 190 ALPMGGRELS 200 QGLLPLPQPY 210 QAQGVLASQA 220 LSQGSEPSSE 230 NANDTIILRN 240 LNPHSTMDSI 250 LGALAPYAVL 260 SSSNVRVIKD 270 KQTQLNRGFA 280 FIQLSTIVEA 290 AQLLQILQAL 300 HPPLTIDGKT 310 INVEFAKGSK 320 RDMASNEGSR 330 INAASVASTA 340 IAAAQWAISQ 350 ASQGGEGAWA 360 TPEEPPVDYS 370 YYQQDEGYGS 380 SQGTDSLYAH 390 GYLKGTKGPG 400 ITGTKGDPAG 410 TGPEASLDPG 420 ADSVSLQAFS 430 RAQPGAAPSL 440 YQQSAAEASS 450 SQGTAANSQP 460 YTIMSPAVLK 470 SELQSPTHPS 480 SALPPATSPT 490 AQESYSQYPV 500 PDVSTYQYDE 510 TSGYYYDPQT 520 GLYYDPNSQY 530 YYNAQSQQYL 540 YWDGERRTYV 550 PALEQSADGH 560 KETGAPSKEG 570 KEKKEKHKTK 580 TAQQIAKDME 590 RWARSLNKQK 600 ENFKNSFQPI 610 SSLRDDERRE 620 SATADAGYAI 630 LEKKGALAER 640 QHTSMDLPKL 650 ASDDRPSPPR 660 GLVAAYSGES 670 DSEEEQERGG 680 PEREEKLTDW 690 QKLACLLCRR 700 QFPSKEALIR 710 HQQLSGLHKQ 720 NLEIHRRAHL 730 SENELEALEK 740 NDMEQMKYRD 750 RAAERREKYG 760 IPEPPEPKRR 770 KYGGISTASV 780 DFEQPTRDGL 790 GSDNIGSRML 800 QAMGWKEGSG 810 LGRKKQGIVT 820 PIEAQTRVRG 830 SGLGARGSSY 840 GVTSTESYKE 850 TLHKTMVTRF NEAQ

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005634	nucleus
Molecular Function	GO:0003723	RNA binding
Molecular Function	GO:0008270	zinc ion binding
Biological Process	GO:0000398	mRNA splicing, via spliceosome
Biological Process	GO:0048255	mRNA stabilization

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.