Search Results
Overview
| Uniprot ID | A0A286XMI9 |
|---|---|
| Protein Name | Transcription initiation factor IIE subunit beta |
| Gene Name | Gtf2e2 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 24 | LSTPVVEKRSLPTES |
Function
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase
Protein Sequence
10
MDPSLLRERE
20
LFKKRALSTP
30
VVEKRSLPTE
40
SSSSSSSSKK
50
KKAKVEHGGS
60
SGSKQNSDHS
70
NGSFNFKALS
80
GSSGYKFGVL
90
AKIVNYMKTR
100
HQRGDTHPLT
110
LEEILDETQH
120
LDIGLKQKQW
130
LMTEALVNNP
140
KIEVIDGKYA
150
FKPKYDLKDK
160
RALLRLLDQH
170
DQRGLGGILL
180
EDIEEGLPNS
190
QKAVKALGDQ
200
ILFVNRPDKK
210
KILFFNDKSC
220
QFSVDEEFQK
230
LWRSVTVDSM
240
DEEKIEEYLK
250
RQGISSMQES
260
GPKKVAPIQR
270
RKKPASQKKR
280
RFKTHNEHMA
290
GVLKDYSDIT
PSK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005673 | transcription factor TFIIE complex |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0001097 | TFIIH-class transcription factor complex binding |
| Biological Process | GO:0006367 | transcription initiation at RNA polymerase II promoter |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.