Search Results
Overview
| Uniprot ID | A0A286XN92 |
|---|---|
| Protein Name | Calcyclin-binding protein |
| Gene Name | Cacybp |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 214 | DMKRTINKAWVESRE |
| 52 | KMQQKSQKKPELHDS |
Function
May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1)
Protein Sequence
10
MASVLEELQN
20
DLEEVKTLLE
30
KATRKRVRDA
40
LTAEKCKIET
50
EIKNKMQQKS
60
QKKPELHDSE
70
KPAAVVAPIT
80
TGYTVKISNY
90
GWDQSDKFVK
100
IYITLTGVHQ
110
VPAENVQVYF
120
TERSFDLLVK
130
NLNGKSYSMI
140
VNNLLKPISV
150
EGSSKKIKTD
160
TVLILCRKKA
170
ENVQWEYLTQ
180
VEKECKEKEK
190
PSYDAETDPS
200
EGLMNVLKKI
210
YEDGDDDMKR
220
TINKAWVESR
230
EKQAKGDTEF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0044548 | S100 protein binding |
| Molecular Function | GO:0015631 | tubulin binding |
| Molecular Function | GO:0031625 | ubiquitin protein ligase binding |
| Biological Process | GO:0007507 | heart development |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.