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Overview

Uniprot IDA0A286XRA9
Protein NameCB1 cannabinoid receptor-interacting protein 1
Gene NameCNRIP1
OrganismCavia porcellus

Kla Sites from experimental identification

Position Flanking peptide
130 VKFYNYHKRDHCQWG
26 NDGPVFYKVDGQRFG
98 TEGVAPTKSGERQPI

Function

Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels

Protein Sequence

10 MGDLPGLVRL 20 SIALRIQPND 30 GPVFYKVDGQ 40 RFGQNRTIKL 50 LTGSSYKVEV 60 KIKPTTLQVE 70 NISIGGVLVP 80 LELKCKEPDG 90 DRVVYTGTYD 100 TEGVAPTKSG 110 ERQPIQITMP 120 FTDIGTFETV 130 WQVKFYNYHK 140 RDHCQWGSPF 150 SVIEYECKPN 160 ETRSLMWVNK ESFL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0098982 GABA-ergic synapse
Cellular Component GO:0098978 glutamatergic synapse
Cellular Component GO:0005886 plasma membrane
Cellular Component GO:0098793 presynapse
Molecular Function GO:0031718 type 1 cannabinoid receptor binding
Biological Process GO:0150036 regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.