Search Results
Overview
| Uniprot ID | A0A286XTG3 |
|---|---|
| Protein Name | Non-selective voltage-gated ion channel VDAC1 |
| Gene Name | Vdac1 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 20 | SARDVFTKGYGFGLI |
| 61 | VTGSLETKYRWTEYG |
Function
Catalyzes the scrambling of phospholipids across the outer mitochondrial membrane; the mechanism is unrelated to channel activity and is capable of translocating both anionic and zwitterionic phospholipids
Protein Sequence
10
MAVPPTYADL
20
GKSARDVFTK
30
GYGFGLIKLD
40
LKTKSENGLE
50
FTSSGSANTE
60
TTKVTGSLET
70
KYRWTEYGLT
80
FTEKWNTDNT
90
LGSEITVEDQ
100
LAHGLKLTFD
110
SSFSPNTGKK
120
NAKIKTGYKR
130
EHINLGCDVD
140
FDIAGPSIRG
150
ALVLGYEGWL
160
AGYQMNFETA
170
KSRVTQSNFA
180
VGYKTDEFQL
190
HTNVNDGTEF
200
GGSIYQKVNK
210
KLETAVNLAW
220
TAGNSNTRFG
230
IAAKYQIDPD
240
ACFSAKVNNS
250
SLIGLGYTQT
260
LKPGIKLTLS
270
ALLDGKNVNA
280
GGHKLGLGLE
FQA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0045121 | membrane raft |
| Cellular Component | GO:0005741 | mitochondrial outer membrane |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0046930 | pore complex |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0015288 | porin activity |
| Molecular Function | GO:0008308 | voltage-gated monoatomic anion channel activity |
| Biological Process | GO:0006915 | apoptotic process |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.