Search Results
Overview
| Uniprot ID | A0A286XTW4 |
|---|---|
| Protein Name | 2-iminobutanoate/2-iminopropanoate deaminase |
| Gene Name | RIDA |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 13 | KKVISTAKAPRPVGA |
Function
Also promotes endoribonucleolytic cleavage of some transcripts by promoting recruitment of the ribonuclease P/MRP complex. Acts by bridging YTHDF2 and the ribonuclease P/MRP complex. RIDA/HRSP12 binds to N6-methyladenosine (m6A)-containing mRNAs containing a 5'-GGUUC-3' motif: cooperative binding of RIDA/HRSP12 and YTHDF2 to such transcripts lead to recruitment of the ribonuclease P/MRP complex and subsequent endoribonucleolytic cleavage
Protein Sequence
10
MTSLIKKVIS
20
TAKAPRPVGA
30
YSQAVLVDRT
40
MYISGQIGID
50
PSSGQLVPGG
60
VVEEAKQAFT
70
NLGEILKAAD
80
CDFTNVVKTS
90
VFLADIKDFA
100
SVNNIYKQYF
110
KSNFPARAAY
120
QVAALPLGAR
130
IEIEAVAVTG
PLTTASL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005777 | peroxisome |
| Molecular Function | GO:0120241 | 2-iminobutanoate/2-iminopropanoate deaminase activity |
| Molecular Function | GO:0003729 | mRNA binding |
| Biological Process | GO:0006629 | lipid metabolic process |
| Biological Process | GO:0006402 | mRNA catabolic process |
| Biological Process | GO:0061157 | mRNA destabilization |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.