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Overview

Uniprot IDA0A286XUV9
Protein NameClathrin light chain
Gene NameCLTB
OrganismCavia porcellus

Kla Sites from experimental identification

Position Flanking peptide
186 QLCDFNPKSSKQCKD

Function

Clathrin is the major protein of the polyhedral coat of coated pits and vesicles

Protein Sequence

10 MADDFGFFSS 20 SESGAAEAAE 30 EDPAAAFLAQ 40 QESEIAGIEN 50 DEGFGAPARA 60 QVASAQPGPS 70 SGAGSEDMGT 80 TVNGDVFQEA 90 NGPADGYAAI 100 AQADRLTQEP 110 ESIRKWREEQ 120 KKRLQELDAA 130 SKVTEQEWRE 140 KAKKDLEEWN 150 QRQSEQVEKN 160 KINNRASEEA 170 FVKESKEDTP 180 GTEWEKVAQL 190 CDFNPKSSKQ 200 CKDVSRLRSV 210 LMSLKQTPLS R

Gene Ontology

Classification GO ID Description
Cellular Component GO:0030132 clathrin coat of coated pit
Cellular Component GO:0030130 clathrin coat of trans-Golgi network vesicle
Cellular Component GO:0099631 postsynaptic endocytic zone cytoplasmic component
Cellular Component GO:0030672 synaptic vesicle membrane
Molecular Function GO:0032050 clathrin heavy chain binding
Molecular Function GO:0005198 structural molecule activity
Biological Process GO:0072583 clathrin-dependent endocytosis
Biological Process GO:0006886 intracellular protein transport

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.