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Overview

Uniprot IDA0A286XVS2
Protein Name14-3-3 protein epsilon
Gene NameYwhae
OrganismCavia porcellus

Kla Sites from experimental identification

Position Flanking peptide
142 FATGNDRKEAAENSL
50 NLLSVAYKNVIGARR
69 IISSIEQKEENKGGE

Function

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Positively regulates phosphorylated protein HSF1 nuclear export to the cytoplasm

Protein Sequence

10 MDDREDLVYQ 20 AKLAEQAERY 30 DEMVESMKKV 40 AGMDVELTVE 50 ERNLLSVAYK 60 NVIGARRASW 70 RIISSIEQKE 80 ENKGGEDKLK 90 MIREYRQMVE 100 TELKLICCDI 110 LDVLDKHLIP 120 AANTGESKVF 130 YYKMKGDYHR 140 YLAEFATGND 150 RKEAAENSLV 160 AYKAASDIAM 170 TELPPTHPIR 180 LGLALNFSVF 190 YYEILNSPDR 200 ACRLAKAAFD 210 DAIAELDTLS 220 EESYKDSTLI 230 MQLLRDNLTL 240 WTSDMQGDGE 250 EQNKEALQDV EDENQ

Gene Ontology

Classification GO ID Description
Molecular Function GO:0004857 enzyme inhibitor activity

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.