Search Results
Overview
| Uniprot ID | A0A286XW70 |
|---|---|
| Protein Name | tRNA-splicing ligase complex subunit ASW |
| Gene Name | C2orf49 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 197 | PVGTTPVKLKRAAPK |
Function
Accessory subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity and may function toward other RNAs
Protein Sequence
10
MAGIVDGRSC
20
TDSELLLHPE
30
LLSQEFLLLT
40
LEQKNIAVEN
50
DVRINKDNLT
60
DLYVQHAIPL
70
PQRELPKNRW
80
GKMMEKKREQ
90
QEIKNEPKRG
100
GTVDGLRKRP
110
LIVFDGCSTS
120
TSIKVKKTEN
130
GDHDRLRPPP
140
RAGIASNVFR
150
KSPNSPSLGL
160
SSTLHTDDKT
170
EHSNSDTKQN
180
HDMRHRKSPP
190
GTMRSPPLSP
200
VGTTPVKLKR
210
AAPKEDTEAL
220
NNLKPPETKR
KIQHVTWP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0072669 | tRNA-splicing ligase complex |
| Biological Process | GO:0048598 | embryonic morphogenesis |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.