Search Results
Overview
| Uniprot ID | A0A286XXA8 |
|---|---|
| Protein Name | Small nuclear ribonucleoprotein E |
| Gene Name | - |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 12 | GQGQKVQKVMVQPIN |
| 9 | VYRGQGQKVQKVMVQ |
Function
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone 3'-end processing
Protein Sequence
10
MVYRGQGQKV
20
QKVMVQPINL
30
IFRYLQNRSQ
40
IQVWLYEQVN
50
MRIEGCIIGF
60
DEYMNLVLDD
70
AEEIHSKTKS
80
RKQLGRIMLK
90
GDNTILLQSV
SN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005681 | spliceosomal complex |
| Cellular Component | GO:0005685 | U1 snRNP |
| Cellular Component | GO:0005686 | U2 snRNP |
| Cellular Component | GO:0005687 | U4 snRNP |
| Cellular Component | GO:0046540 | U4/U6 x U5 tri-snRNP complex |
| Cellular Component | GO:0005682 | U5 snRNP |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0000387 | spliceosomal snRNP assembly |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.