Search Results
Overview
| Uniprot ID | A0A286XYG9 |
|---|---|
| Protein Name | peptidylprolyl isomerase |
| Gene Name | FKBP3 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 80 | KGTESVSKVTDQVKN |
| 86 | SKVTDQVKNVKLNEE |
| 89 | TDQVKNVKLNEEKPK |
Function
FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins
Protein Sequence
10
MAAAVPQRAW
20
TVEQLRSEQL
30
PKKDIIKFLQ
40
EHGSDSFLAE
50
HKLLGNIKNV
60
AKTANKDHLV
70
TAYNHLFETK
80
RFKGTESVSK
90
VTDQVKNVKL
100
NEEKPKETKS
110
EETQDEGPPK
120
YTKSILKKGD
130
KTNFPKKGDV
140
VHCWYTGTLQ
150
DGTVFDTNIQ
160
TSAKKKKNAK
170
PLSFKVGVGK
180
VIRGWDEALL
190
TMSKGEKARL
200
EIEPEWAYGK
210
KGQPDAKIPP
220
NAKLIFEVEL
VDID
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005634 | nucleus |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.