Search Results
Overview
| Uniprot ID | A0A286XZ43 |
|---|---|
| Protein Name | Polymerase delta-interacting protein 3 |
| Gene Name | POLDIP3 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 214 | LPASVRTKALTHVSR |
Function
Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by association with the TREX complex
Protein Sequence
10
MADISLDELI
20
RKRGVATKGR
30
LSTRPGLGGV
40
RSRVGVQPSL
50
LSPPTRTATF
60
QQRFDARQKI
70
GLADARLKLG
80
VKDAREKLLQ
90
KDARFRIKGK
100
VQDAREMLNS
110
RKQQSAVAQR
120
PRQVADAREK
130
ISLKRSTPAA
140
YPSLPVGTVT
150
PALKLTKTIQ
160
NLHDLDEEEE
170
EVAAHVPTKQ
180
MKFAASGSFL
190
HHVVRSHSKA
200
LPLTKVVQND
210
AYTAPALPAS
220
VRTKALTHVS
230
RTLVNKEEPP
240
KELPPAEPVL
250
SPLEGTKMTV
260
NNLHPRVTEE
270
DIVELFCVCG
280
ALKRARLVHP
290
GVAEVVFVKK
300
DDAITAYKKY
310
NNRCLDGQPM
320
KCNLHMNGNV
330
ITSDQPILLR
340
LSDSPLVKKD
350
SELPRRLPSA
360
ASANPPAEVD
370
PDTILKALFK
380
SSGASVTTQP
TEFKIKL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0016607 | nuclear speck |
| Molecular Function | GO:0003729 | mRNA binding |
| Biological Process | GO:0016973 | poly(A)+ mRNA export from nucleus |
| Biological Process | GO:0006417 | regulation of translation |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.