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Overview

Uniprot IDA0A286XZW3
Protein NameGlia maturation factor
Gene NameGMFB
OrganismCavia porcellus

Kla Sites from experimental identification

Position Flanking peptide
25 LRKFRFRKETNNAAI

Function

This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells

Protein Sequence

10 MSESLVVCDV 20 AEDLVEKLRK 30 FRFRKETNNA 40 AIIMKIDKDK 50 RLVVLDEELE 60 GISPDELKDE 70 LPERQPRFIV 80 YSYKYQHDDG 90 RVSYPLCFIF 100 SSPVGCKPEQ 110 QMMYAGSKNK 120 LVQTAELTKV 130 FEIRNTEDLT 140 EEWLREKLGF FH

Gene Ontology

Classification GO ID Description
Cellular Component GO:0030864 cortical actin cytoskeleton
Molecular Function GO:0003779 actin binding
Molecular Function GO:0071933 Arp2/3 complex binding
Molecular Function GO:0008083 growth factor activity
Biological Process GO:0071846 actin filament debranching
Biological Process GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.