Search Results

Overview

Uniprot IDA0A286Y1B9
Protein NameProtein sprouty homolog 2
Gene NameSPRY2
OrganismCavia porcellus

Kla Sites from experimental identification

Position Flanking peptide
160 VQPKSELKPGELKPL

Function

No function data available.

Protein Sequence

10 METRAQSGNG 20 SQPLLQAPRD 30 SGRPRGEPDP 40 RDALAQQVHV 50 LSLDQIRAIR 60 NTNEYTEGPT 70 VVPRPGLKPA 80 PRPSTQHKHE 90 RLHGLPEHRQ 100 APRLQHSQVH 110 SSARGAPLSR 120 SISTVSSGSR 130 NSTRTSTSSS 140 SSEQRLLGSS 150 FSSGPLTDGI 160 IRVQPKSELK 170 PGELKPLSKE 180 DLGLHAYRCE 190 DCGKCKCKEC 200 TYPRPLPSDW 210 ICDKQCLCSA 220 QNVIDYGTCV 230 CCVKGLFYHC 240 SNDDEDNCAD 250 NPCSCSQSHC 260 CTRWSAMGVM 270 SLFLPCLWCY 280 LPAKGCLKLC 290 QGCYDRVNRP 300 GCRCKNSNTV 310 CCKVPAVPPR NFEKPT

Gene Ontology

Classification GO ID Description
Cellular Component GO:0015629 actin cytoskeleton
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Cellular Component GO:0005829 cytosol
Cellular Component GO:0015630 microtubule cytoskeleton
Cellular Component GO:0005634 nucleus
Cellular Component GO:0032587 ruffle membrane
Molecular Function GO:0019901 protein kinase binding
Molecular Function GO:0043539 protein serine/threonine kinase activator activity
Molecular Function GO:0030291 protein serine/threonine kinase inhibitor activity
Biological Process GO:0048513 animal organ development
Biological Process GO:0035924 cellular response to vascular endothelial growth factor stimulus
Biological Process GO:0016525 negative regulation of angiogenesis
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0031345 negative regulation of cell projection organization
Biological Process GO:0010719 negative regulation of epithelial to mesenchymal transition
Biological Process GO:0070373 negative regulation of ERK1 and ERK2 cascade
Biological Process GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway
Biological Process GO:1902747 negative regulation of lens fiber cell differentiation
Biological Process GO:0031397 negative regulation of protein ubiquitination
Biological Process GO:0046580 negative regulation of Ras protein signal transduction
Biological Process GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
Biological Process GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.