Search Results
Overview
| Uniprot ID | A0A286Y2Y5 |
|---|---|
| Protein Name | Peroxiredoxin-6 |
| Gene Name | PRDX6 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 204 | EAKKLFPKGVFTKEL |
| 209 | FPKGVFTKELPSGKK |
Function
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively
Protein Sequence
10
MPGGLLLGDE
20
APNFEANTTI
30
GRIRFHDFLG
40
DSWGILFSHP
50
RDFTPVCTTE
60
LGRAAKLTPE
70
FAKRNVKLIA
80
LSIDSVEDHL
90
AWSKDINAYN
100
GDEPTEKLPF
110
PIIDDKNRDL
120
AILLGMLDPA
130
EKDEKGMPVT
140
ARVVFIFGPD
150
KKLKLSILYP
160
ATTGRNFDEI
170
LRVVISLQLT
180
AEKRVATPVD
190
WKDGDSVMVL
200
PTIPEEEAKK
210
LFPKGVFTKE
220
LPSGKKYLRY
TPQP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0004602 | glutathione peroxidase activity |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0051920 | peroxiredoxin activity |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Molecular Function | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity |
| Molecular Function | GO:0004623 | A2-type glycerophospholipase activity |
| Molecular Function | GO:0031625 | ubiquitin protein ligase binding |
| Biological Process | GO:0045454 | cell redox homeostasis |
| Biological Process | GO:0046475 | glycerophospholipid catabolic process |
| Biological Process | GO:0048026 | positive regulation of mRNA splicing, via spliceosome |
| Biological Process | GO:0006979 | response to oxidative stress |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.