Search Results

Overview

Uniprot IDA0A286Y5D3
Protein NameBeta-arrestin-2
Gene NameARRB2
OrganismCavia porcellus

Kla Sites from experimental identification

Position Flanking peptide
327 VSYRVKVKLVVSRGG

Function

No function data available.

Protein Sequence

10 AFPFCFIRVF 20 KKSSPNCKLT 30 VYLGKRDFVD 40 HLDKVDPVDG 50 VVLVDPDYLK 60 DRKVFVTLTC 70 AFRYGREDLD 80 VLGLSFRKDL 90 FIATYQAFPP 100 VPNPPRPLTR 110 LQDRLLRKLG 120 QHAHPFFFTI 130 PQNLPCSVTL 140 QPGPEDTGKA 150 CGVDFEIRAF 160 CAKSLEEKSH 170 KRNSVRLVIR 180 KVQFAPEKPG 190 PQPSAETTRH 200 FLMSDRLLHL 210 EASLDKELYY 220 HGEPLSVNVH 230 VTNNSSKTVK 240 KIRVSVRQYA 250 DICLFSTAQY 260 KCPVAQLEQD 270 DQVSPSSTFC 280 KVYTITPLLS 290 DNREKRGLAL 300 DGKLKHEDTN 310 LASSTIVKEG 320 ANKEVLGILV 330 SYRVKVKLVV 340 SRGGDVSVEL 350 PFVLMHPKPH 360 DHIPLTQTHP 370 PALPSPPTAA 380 PETDVPVDTN 390 LIEFDTNYAT 400 DDDIVFEDFA 410 RLRLKGMKDD DYDDHFC

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005905 clathrin-coated pit
Cellular Component GO:0005829 cytosol
Cellular Component GO:0030139 endocytic vesicle
Cellular Component GO:0098978 glutamatergic synapse
Cellular Component GO:0005634 nucleus
Cellular Component GO:0005886 plasma membrane
Molecular Function GO:0031701 angiotensin receptor binding
Molecular Function GO:0031748 D1 dopamine receptor binding
Molecular Function GO:0043422 protein kinase B binding
Molecular Function GO:0030674 protein-macromolecule adaptor activity
Molecular Function GO:0031625 ubiquitin protein ligase binding
Biological Process GO:0007628 adult walking behavior
Biological Process GO:0060326 cell chemotaxis
Biological Process GO:0070098 chemokine-mediated signaling pathway
Biological Process GO:0002031 G protein-coupled receptor internalization
Biological Process GO:0043124 negative regulation of canonical NF-kappaB signal transduction
Biological Process GO:0032691 negative regulation of interleukin-1 beta production
Biological Process GO:0032695 negative regulation of interleukin-12 production
Biological Process GO:0032715 negative regulation of interleukin-6 production
Biological Process GO:0045953 negative regulation of natural killer cell mediated cytotoxicity
Biological Process GO:0034122 negative regulation of toll-like receptor signaling pathway
Biological Process GO:0032720 negative regulation of tumor necrosis factor production
Biological Process GO:2000727 positive regulation of cardiac muscle cell differentiation
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Biological Process GO:0002092 positive regulation of receptor internalization
Biological Process GO:0032226 positive regulation of synaptic transmission, dopaminergic
Biological Process GO:0098926 postsynaptic signal transduction
Biological Process GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
Biological Process GO:0015031 protein transport
Biological Process GO:0016567 protein ubiquitination
Biological Process GO:0006366 transcription by RNA polymerase II
Biological Process GO:0007179 transforming growth factor beta receptor signaling pathway

Reference

[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.