Search Results
Overview
| Uniprot ID | A0A286Y5I8 |
|---|---|
| Protein Name | Hsp90 co-chaperone Cdc37 |
| Gene Name | CDC37 |
| Organism | Cavia porcellus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 121 | WNVDTLSKDGFSKSM |
Function
Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity
Protein Sequence
10
MVDYSVWDHI
20
EVSDDEDETH
30
PNIDTASLFR
40
WRHQARVERM
50
EQFQKEKEEL
60
DRGCRECKRK
70
VAECQRKLKE
80
LEVAEGGQAE
90
LERLQAEAQQ
100
LRKEERSWEQ
110
KLEEMRKKEK
120
SMPWNVDTLS
130
KDGFSKSMVN
140
TKPEKAEEES
150
EEVREQKHKT
160
FVEKYEKQIK
170
HFGMLRRWDD
180
SQKYLSDNVH
190
LVCEETANYL
200
VIWCIDLEVE
210
EKCALMEQVA
220
HQTIVMQFIL
230
ELAKSLKVDP
240
RACFRQFFTK
250
IKTADRQYME
260
GFNDELEAFK
270
ERVRGRAKLR
280
IEKAMKEYEE
290
EERRKRLGPG
300
GLDPVEVYES
310
LPEELQKCFD
320
VKDVQMLQDA
330
ISKMDPTDAK
340
YHMQRCIDSG
350
LWVPNSKASE
360
PKEGEEAGPR
370
DPLLDTVTKP
GDEKDGSA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:1990565 | HSP90-CDC37 chaperone complex |
| Molecular Function | GO:0051879 | Hsp90 protein binding |
| Molecular Function | GO:0019901 | protein kinase binding |
| Molecular Function | GO:0019887 | protein kinase regulator activity |
| Molecular Function | GO:0051087 | protein-folding chaperone binding |
| Molecular Function | GO:0097110 | scaffold protein binding |
| Molecular Function | GO:0051082 | unfolded protein binding |
| Biological Process | GO:1905091 | positive regulation of type 2 mitophagy |
| Biological Process | GO:0010608 | post-transcriptional regulation of gene expression |
| Biological Process | GO:0006457 | protein folding |
| Biological Process | GO:0050821 | protein stabilization |
Reference
[1] Feng J, Chen X, Li R, Xie Y, Zhang X et al.. Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia.. iScience 27(9):110606. 2024 Sep 20. PMID: 39246443.