Search Results
Overview
| Uniprot ID | A0A286ZHZ3 |
|---|---|
| Protein Name | Translin |
| Gene Name | TSN |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 219 | LSIRGFNKETVAACS |
| 76 | KTHLTSLKTKFPAEQ |
| 78 | HLTSLKTKFPAEQYY |
Function
DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots
Protein Sequence
10
MSVSEIFVEL
20
QGFLAAEQDI
30
REEIRKVVQS
40
LEQTAREILT
50
LLQGVHQGAG
60
FQDIPKRCLK
70
AREHFGTVKT
80
HLTSLKTKFP
90
AEQYYRFHEH
100
WRFVLQRLVF
110
LAAFVVYLES
120
ETLVTREAVT
130
EILGIEPDRE
140
KGFHLDVEDY
150
LSGVLILASE
160
LSRLSVNSVT
170
AGDYARPLHI
180
STFINELDSG
190
FRLLNLKNDS
200
LRKRYDGLKY
210
DVKKVEEVVY
220
DLSIRGFNKE
TVAACSEK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0004519 | endonuclease activity |
| Molecular Function | GO:0016787 | hydrolase activity |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0043565 | sequence-specific DNA binding |
| Molecular Function | GO:0003697 | single-stranded DNA binding |
| Biological Process | GO:0030422 | siRNA processing |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.