Search Results
Overview
| Uniprot ID | A0A286ZJ16 |
|---|---|
| Protein Name | Septin |
| Gene Name | SEPTIN7 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 150 | FMKRLHEKVNIIPLI |
| 172 | PEECQQFKKQIMKEI |
| 177 | QFKKQIMKEIQEHKI |
| 183 | MKEIQEHKIKIYEFP |
| 337 | KEKVQKLKDSEAELQ |
| 53 | GPSHRIKKTVQVEQS |
| 61 | TVQVEQSKVLIKEGG |
Function
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation
Protein Sequence
10
MSVSARSAAA
20
EERSVNSSTM
30
GESGLGKSTL
40
INSLFLTDLY
50
SPEYPGPSHR
60
IKKTVQVEQS
70
KVLIKEGGVQ
80
LLLTIVDTPG
90
FGDAVDNSNC
100
WQPVIDYIDS
110
KFEDYLNAES
120
RVNRRQMPDN
130
RVQCCLYFIA
140
PSGHGLKPLD
150
IEFMKRLHEK
160
VNIIPLIAKA
170
DTLTPEECQQ
180
FKKQIMKEIQ
190
EHKIKIYEFP
200
ETDDEEENKL
210
VKKIKDRLPL
220
AVVGSNTIIE
230
VNGKRVRGRQ
240
YPWGVAEVEN
250
GEHCDFTILR
260
NMLIRTHMQD
270
LKDVTNNVHY
280
ENYRSRKLAA
290
VTYNGVDNNK
300
NKGQLTKSPL
310
AQMEEERREH
320
VAKMKKMEME
330
MEQVFEMKVK
340
EKVQKLKDSE
350
AELQRRHEQM
360
KKNLEAQHKE
370
LEEKRRQFED
380
EKANWEAQQR
390
ILEQQNSSRT
400
LEKNKKKGKI
F
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005930 | axoneme |
| Cellular Component | GO:0032154 | cleavage furrow |
| Cellular Component | GO:0000776 | kinetochore |
| Cellular Component | GO:0030496 | midbody |
| Cellular Component | GO:0031105 | septin complex |
| Cellular Component | GO:0005819 | spindle |
| Molecular Function | GO:0005525 | GTP binding |
| Biological Process | GO:0051301 | cell division |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.