Search Results

Overview

Uniprot IDA0A286ZL51
Protein NameLarge ribosomal subunit protein uL23
Gene NameRPL23A
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
110 KANKHQIKQAVKKLY
115 QIKQAVKKLYDIDVA
134 LIRPDGEKKAYVRLA
14 KEAPAPPKAEAKAKA
7 *MAPKAKKEAPAPPK
70 KSAPRRNKLDHYAII
88 LTTESAMKKIEDNNT

Function

Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA. May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination

Protein Sequence

10 MAPKAKKEAP 20 APPKAEAKAK 30 ALKAKKAVLK 40 GVHSHKKKKI 50 RTSPTFRRPK 60 TLRLRRQPKY 70 PRKSAPRRNK 80 LDHYAIIKFP 90 LTTESAMKKI 100 EDNNTLVFIV 110 DVKANKHQIK 120 QAVKKLYDID 130 VAKVNTLIRP 140 DGEKKAYVRL 150 APDYDALDVA NKIGII

Gene Ontology

Classification GO ID Description
Cellular Component GO:0022625 cytosolic large ribosomal subunit
Cellular Component GO:0005634 nucleus
Molecular Function GO:0019843 rRNA binding
Molecular Function GO:0003735 structural constituent of ribosome
Biological Process GO:0006412 translation

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.