Search Results
Overview
| Uniprot ID | A0A286ZNH3 |
|---|---|
| Protein Name | 2-iminobutanoate/2-iminopropanoate deaminase |
| Gene Name | RIDA |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 117 | YQVAALPKGGRVEIE |
| 7 | *MSALVRKVISTVKA |
Function
Also promotes endoribonucleolytic cleavage of some transcripts by promoting recruitment of the ribonuclease P/MRP complex. Acts by bridging YTHDF2 and the ribonuclease P/MRP complex. RIDA/HRSP12 binds to N6-methyladenosine (m6A)-containing mRNAs containing a 5'-GGUUC-3' motif: cooperative binding of RIDA/HRSP12 and YTHDF2 to such transcripts lead to recruitment of the ribonuclease P/MRP complex and subsequent endoribonucleolytic cleavage
Protein Sequence
10
MSALVRKVIS
20
TVKAPAAIGP
30
YSQAVLVDRT
40
IYISGQIGMD
50
PASGQLVPGG
60
VVEEAKQALT
70
NMGEILKAAG
80
CDFTNVVKTT
90
VLLADINDFS
100
TVNDIYKQYF
110
QGNFPARAAY
120
QVAALPKGGR
130
VEIEAIAIQG
PLVTASL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005777 | peroxisome |
| Molecular Function | GO:0120241 | 2-iminobutanoate/2-iminopropanoate deaminase activity |
| Molecular Function | GO:0019239 | deaminase activity |
| Molecular Function | GO:0003729 | mRNA binding |
| Biological Process | GO:0006629 | lipid metabolic process |
| Biological Process | GO:0006402 | mRNA catabolic process |
| Biological Process | GO:0061157 | mRNA destabilization |
| Biological Process | GO:0017148 | negative regulation of translation |
| Cellular Component | GO:0005739 | mitochondrion |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.