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Overview

Uniprot ID	A0A286ZQS7
Protein Name	Sec1 family domain-containing protein 1
Gene Name	SCFD1
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
309	RPKRKNKKSYDLTPV
425	YEEKIMSKTTLDKSL

Function

Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi

Protein Sequence

10 MAAAAAASIR 20 ERQTVALKRM 30 LNFNVPHVKN 40 SAGEPVWKVL 50 IYDRFGQDII 60 SPLLSVKELR 70 DMGITLHLLL 80 HSDRDPIPDV 90 PAVYFVMPTE 100 ENIDRLCQDL 110 RNQLYESYYL 120 NFISAISRSK 130 LEDIANAALA 140 ASAVTQVAKV 150 FDQYLNFITL 160 EDDMFVLCNQ 170 NKEIVSYRAI 180 NRTDITDTEM 190 ETVMDTIVDS 200 LFCFFVTLGA 210 VPIIRCSRGT 220 AAEMVAVKLD 230 KKLRENLRDA 240 RNSLFTGDTL 250 GAGQFSFQRP 260 LLVLVDRNID 270 LATPLHHTWT 280 YQALVHDVLD 290 FHLNRVNLEE 300 SSGTETSPAG 310 ARPKRKNKKS 320 YDLTPVDKFW 330 QKHKGSPFPE 340 VAESVQQELE 350 SYRAQEDEVK 360 RLKSIMGLEG 370 EDEGAISMLS 380 DNTAKLTSAV 390 SSLPELLEKK 400 RLIDLHTNVA 410 TAVLEHIKAR 420 KLDVYFEYEE 430 KIMSKTTLDK 440 SLLDIISDPD 450 AGTPEDKMRL 460 FLIYYISAQQ 470 APSEADLEQY 480 KKALTDAGCN 490 LNPLQYIKQW 500 KAFAKMASAP 510 ASYGNTTTKP 520 MGLLSRVMNT 530 GSQFVMEGVK 540 NLVLKQQNLP 550 VTRILDNLME 560 MKSNPETDDY 570 RYFDPKMLRG 580 NDSSVPRNKN 590 PFQEAIVFVV 600 GGGNYIEYQN 610 LVDYIKGKQG 620 KHILYGCSEL 630 FNATQFIKQL SQLGQK

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0032580	Golgi cisterna membrane
Biological Process	GO:0015031	protein transport
Biological Process	GO:0016192	vesicle-mediated transport

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.