Search Results
Overview
| Uniprot ID | A0A286ZRJ3 |
|---|---|
| Protein Name | Electron transfer flavoprotein subunit alpha |
| Gene Name | ETFA |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 164 | VKCDEKVKVFSVRGT |
| 206 | WLDQKLTKSDRPELT |
| 216 | RPELTGAKVVVSGGR |
| 294 | LAGMKDSKTIVAINK |
| 59 | SCLVAGTKCDKVAQD |
| 62 | VAGTKCDKVAQDLCK |
| 69 | KVAQDLCKVAGVAKV |
| 75 | CKVAGVAKVLVAQHD |
Function
Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism
Protein Sequence
10
MFRAVAPVHL
20
RRAASSLRFQ
30
STLVIAEHAN
40
DTLAPITLNT
50
ITAAKRLGGE
60
VSCLVAGTKC
70
DKVAQDLCKV
80
AGVAKVLVAQ
90
HDAYKGLLPE
100
ELTPLVLATQ
110
KQFNYTHICA
120
GASAFGKNLL
130
PRIAAKLDVA
140
PISDIIAIKS
150
PDTFVRPIYA
160
GNALCTVKCD
170
EKVKVFSVRG
180
TSFEAAATSG
190
GSAISEKASS
200
ASPVGISEWL
210
DQKLTKSDRP
220
ELTGAKVVVS
230
GGRGLKSGEN
240
FKLLYDLADQ
250
LHAAVGASRA
260
AVDAGFVPND
270
MQVGQTGKIV
280
APELYIAVGI
290
SGAIQHLAGM
300
KDSKTIVAIN
310
KDPEAPIFQV
320
ADYGIVADLF
330
KGGTCSMWKF
340
PARGQIGAVA
350
ANLHHGSWQR
360
QILNPLSKAR
DQASPRPLG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0045251 | electron transfer flavoprotein complex |
| Cellular Component | GO:0005759 | mitochondrial matrix |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0009055 | electron transfer activity |
| Molecular Function | GO:0050660 | flavin adenine dinucleotide binding |
| Molecular Function | GO:0016491 | oxidoreductase activity |
| Biological Process | GO:0009063 | amino acid catabolic process |
| Biological Process | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase |
| Biological Process | GO:0022904 | respiratory electron transport chain |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.