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Overview

Uniprot IDA0A286ZS14
Protein NameSodium/potassium-transporting ATPase subunit beta
Gene NameATP1B3
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
139 MNRIIGLKPQGEPRI
94 DGKFLEQKGPHYDAC

Function

This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known

Protein Sequence

10 MTKKEKKSFN 20 QSMAEWKLFL 30 YNPTTGEFLG 40 RSAKSWGLMV 50 FPKPVSALDY 60 SFSVSDPDSY 70 KGYIDDLKKF 80 LKPYDLEEQK 90 NLTDCTDGKF 100 LEQKGPHYDA 110 CRFPLNLLEA 120 CSGEIDPQFG 130 YSRGNPCILV 140 KMNRIIGLKP 150 QGEPRIECIS 160 KGESTAVLST 170 YPPNGKIDIK 180 YFPYYGKKLH 190 GNYLQPLVAV 200 QLTFDAGNDM 210 NEVTVECKID 220 GSPNLKNQDD 230 RDKFLGRVAF KVTVHA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0016324 apical plasma membrane
Cellular Component GO:0016323 basolateral plasma membrane
Cellular Component GO:0005890 sodium:potassium-exchanging ATPase complex
Biological Process GO:0006813 potassium ion transport
Biological Process GO:0006814 sodium ion transport

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.