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Overview

Uniprot ID	A0A286ZSD6
Protein Name	Glycerol-3-phosphate dehydrogenase
Gene Name	GPD2
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
159	GTSSRSTKLIHGGVR
317	RVSGARCKDVLTGQE

Function

Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device

Protein Sequence

10 ISWAAPAAYG 20 GSERDSSCWR 30 RCSCHYSRPL 40 SVCSLQKEAI 50 PVRKLMGKED 60 ECLLTSFDCV 70 HLQGMRFMFT 80 NGIHTPSPLQ 90 VNLAFVEAAD 100 CVSEPVNREP 110 PSREAQILTL 120 KNTTEFDVLV 130 IGGGATGSGC 140 ALDAVTRGLK 150 TALVERDDFS 160 SGTSSRSTKL 170 IHGGVRYLQK 180 AIMKLDIEQY 190 RMVKEALHER 200 ANLLEIAPHL 210 SAPLPIMLPI 220 YKWWQLPYYW 230 VGIKLYDLVA 240 GSNCLKSSYV 250 LSKSRALEHF 260 PMLQKDKLVG 270 AIVYYDGQHN 280 DARMNLAIAL 290 TAARYGAATA 300 NYMEVVSLLK 310 KTDPQTGKER 320 VSGARCKDVL 330 TGQEFDVRAK 340 CVINATGPFT 350 DTVRRMDDKD 360 ATAICQPSAG 370 VHIVMPGYYS 380 PESMGLLDPA 390 TSDGRVIFFL 400 PWQKMTIAGT 410 TDTPTDVTNH 420 PIPSEEDINF 430 ILNEVRNYLS 440 SDVEVRRGDV 450 LAAWSGIRPL 460 VTDPKSADTQ 470 SISRNHVVDI 480 SESGLITIAG 490 GKWTTYRSMA 500 EDTINAAVKA 510 HNLNAGPSRT 520 VGLFLQGGKD 530 WSPTLYIRLV 540 QDYGLESEVA 550 QHLAATYGDK 560 AFEVAKMASV 570 TGKRWPIVGV 580 RLVSEFPYIE 590 AEVKYGIKEY 600 ACTAVDMISR 610 RTRLAFLNVQ 620 AAEEALPRIV 630 ELMGRELNWN 640 DSKKEEELET 650 ARKFLYYEMG 660 YKSRSEQLTD 670 RSEISLLPSD 680 IDRYKKRFHK 690 FDADQKGFIT 700 IVDVQRVLES 710 INVQMDENTL 720 HEILNEVDLN 730 KNGQVELNEF 740 LQLMSAIQKG 750 RVSGSRLAIL 760 MKTAEENLDR 770 RVPIPVDRSC GGL

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005743	mitochondrial inner membrane
Molecular Function	GO:0005509	calcium ion binding
Molecular Function	GO:0004368	glycerol-3-phosphate dehydrogenase (quinone) activity
Biological Process	GO:0006072	glycerol-3-phosphate metabolic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.